| 蒙塔诺瓦资本MONTANOVA CAPITAL, LLC |
| 9.37% | 6.72% | #3 | $5.13亿 | 416.9万股 | $2.63亿 | 416.9万股 | 00.00% | 持仓不变 |
| 富达投资FMR LLC |
| 0.02% | 0.01% | #55 | $3.94亿 | 320.5万股 | $1.13亿 | 179.3万股 | +141.2万股+78.76% | 加仓 |
| SR ONE CAPITAL MANAGEMENT, LP |
| 28.42% | 16.57% | #1 | $2.95亿 | 240.2万股 | $1.52亿 | 240.2万股 | 00.00% | 持仓不变 |
| 深轨资本Deep Track Capital, LP |
| 3.58% | 0.52% | #6 | $2.46亿 | 200.0万股 | $3,157.5万 | 50.0万股 | +150.0万股+300.00% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| 0.03% | 0.02% | #45 | $2.31亿 | 187.8万股 | $1.15亿 | 182.6万股 | +5.2万股+2.85% | 加仓 |
| Siren, L.L.C. |
| 4.12% | 2.64% | #5 | $2.04亿 | 165.5万股 | $9,506.4万 | 150.5万股 | +15.0万股+9.96% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #84 | $1.96亿 | 159.4万股 | $1,784.7万 | 28.3万股 | +131.1万股+463.95% | 加仓 |
| 维京全球投资VIKING GLOBAL INVESTORS LP |
| 0.55% | 0.3% | #20 | $1.92亿 | 156.1万股 | $1.07亿 | 169.1万股 | -12.9万股-7.63% | 减仓 |
| 摩根大通JPMORGAN CHASE & CO |
| 0.01% | <0.01% | #65 | $1.44亿 | 116.6万股 | $5,940.0万 | 97.6万股 | +18.9万股+19.40% | 加仓 |
| 安本标准投资Aberdeen Group plc |
| 0.19% | 0.11% | #26 | $1.35亿 | 109.7万股 | $6,660.2万 | 105.5万股 | +4.2万股+3.98% | 加仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.06% | 0.01% | #37 | $1.25亿 | 101.4万股 | $847.6万 | 13.4万股 | +87.9万股+655.22% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #92 | $1.07亿 | 86.9万股 | $4,418.3万 | 70.0万股 | +17.0万股+24.24% | 加仓 |
| Maverick资本MAVERICK CAPITAL LTD |
| 0.86% | — | #15 | $9,712.0万 | 79.0万股 | $0 | 0股 | +79.0万股 | 新买入 |
| 詹尼森联营JENNISON ASSOCIATES LLC |
| 0.06% | 0.01% | #39 | $9,204.2万 | 74.9万股 | $895.3万 | 14.2万股 | +60.7万股+428.05% | 加仓 |
| INFINITUM ASSET MANAGEMENT, LLC |
| 9.14% | 5.77% | #4 | $8,988.7万 | 73.1万股 | $4,617.2万 | 73.1万股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| 0.01% | <0.01% | #62 | $8,245.9万 | 67.1万股 | $2,191.8万 | 34.7万股 | +32.4万股+93.25% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| 0.06% | 0.04% | #38 | $7,198.9万 | 58.6万股 | $4,133.8万 | 65.5万股 | -6.9万股-10.55% | 减仓 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| 0.09% | 0.11% | #36 | $6,758.1万 | 55.0万股 | $6,946.5万 | 110.0万股 | -55.0万股-50.03% | 减仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #98 | $6,692.5万 | 54.4万股 | $469.8万 | 7.4万股 | +47.0万股+631.68% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #82 | $6,247.7万 | 50.8万股 | $1,126.0万 | 17.8万股 | +33.0万股+185.10% | 加仓 |
| Woodline合伙人Woodline Partners LP |
| 0.19% | 0.12% | #25 | $6,166.5万 | 50.2万股 | $3,161.6万 | 50.1万股 | +944股+0.19% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| 0.01% | <0.01% | #69 | $4,260.9万 | 34.7万股 | $23.2万 | 3,668股 | +34.3万股+9,348.88% | 加仓 |
| Stifel金融STIFEL FINANCIAL CORP |
| 0.03% | 0.02% | #42 | $3,615.9万 | 29.4万股 | $1,857.3万 | 29.4万股 | 00.00% | 持仓不变 |
| EMERALD ADVISERS, LLC |
| 0.83% | 0.26% | #16 | $3,545.2万 | 28.8万股 | $837.0万 | 13.3万股 | +15.6万股+117.58% | 加仓 |
| Frontier资本管理FRONTIER CAPITAL MANAGEMENT CO LLC |
| 0.29% | — | #22 | $3,133.4万 | 25.5万股 | $0 | 0股 | +25.5万股 | 新买入 |
| BAMCO(巴伦基金)BAMCO INC /NY/ |
| 0.04% | 0.01% | #41 | $2,822.5万 | 23.0万股 | $376.8万 | 6.0万股 | +17.0万股+284.76% | 加仓 |
| EMERALD MUTUAL FUND ADVISERS 信托EMERALD MUTUAL FUND ADVISERS TRUST |
| 0.91% | 0.33% | #14 | $2,580.8万 | 21.0万股 | $690.1万 | 10.9万股 | +10.1万股+92.09% | 加仓 |
| Logos Global Management LP |
| 0.95% | 0.08% | #12 | $2,212.9万 | 18.0万股 | $157.9万 | 2.5万股 | +15.5万股+620.00% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #90 | $2,189.7万 | 17.8万股 | $218.1万 | 3.5万股 | +14.4万股+415.71% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #86 | $2,117.0万 | 17.2万股 | $618.9万 | 9.8万股 | +7.4万股+75.70% | 加仓 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| 0.03% | 0.04% | #47 | $2,076.9万 | 16.9万股 | $3,365.3万 | 53.3万股 | -36.4万股-68.30% | 减仓 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | 0.01% | #81 | $1,851.0万 | 15.1万股 | $3,246.1万 | 51.4万股 | -36.3万股-70.71% | 减仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #114 | $1,832.5万 | 14.9万股 | $28.7万 | 4,537股 | +14.5万股+3,185.30% | 加仓 |
| Sofinnova Investments, Inc. |
| 0.95% | 0.18% | #13 | $1,831.7万 | 14.9万股 | $463.0万 | 7.3万股 | +7.6万股+103.22% | 加仓 |
| MFS马萨诸塞金融服务MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
| 0.01% | — | #73 | $1,817.6万 | 14.8万股 | $0 | 0股 | +14.8万股 | 新买入 |
| Kalehua Capital Management LLC |
| 12.84% | 6.51% | #2 | $1,791.2万 | 14.6万股 | $920.1万 | 14.6万股 | 00.00% | 持仓不变 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #79 | $1,736.2万 | 14.1万股 | $618.8万 | 9.8万股 | +4.3万股+44.13% | 加仓 |
| Ensign Peak顾问Ensign Peak Advisors, Inc |
| 0.03% | 0.02% | #48 | $1,572.0万 | 12.8万股 | $947.3万 | 15.0万股 | -2.2万股-14.75% | 减仓 |
| SEVEN GRAND MANAGERS, LLC |
| 0.62% | 0.32% | #17 | $1,536.8万 | 12.5万股 | $472.0万 | 7.5万股 | +5.0万股+67.22% | 加仓 |
| MASTERS 资本管理MASTERS CAPITAL MANAGEMENT LLC |
| 0.32% | 0.21% | #21 | $1,229.4万 | 10.0万股 | $631.5万 | 10.0万股 | 00.00% | 持仓不变 |
| MYDA Advisors LLC |
| 1.83% | 1.25% | #7 | $1,229.4万 | 10.0万股 | $757.8万 | 12.0万股 | -2.0万股-16.67% | 减仓 |
| Affinity Asset Advisors, LLC |
| 0.56% | 0.23% | #19 | $1,229.4万 | 10.0万股 | $442.1万 | 7.0万股 | +3.0万股+42.86% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | <0.01% | #91 | $1,180.9万 | 9.6万股 | $1,263.0万 | 20.0万股 | -10.4万股-51.97% | 减仓 |
| SILVERARC CAPITAL MANAGEMENT, LLC |
| 1.21% | — | #10 | $1,167.9万 | 9.5万股 | $0 | 0股 | +9.5万股 | 新买入 |
| 吉尔德·加尼翁·豪GILDER GAGNON HOWE & CO LLC |
| 0.12% | — | #34 | $1,166.3万 | 9.5万股 | $0 | 0股 | +9.5万股 | 新买入 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.01% | — | #58 | $1,006.3万 | 8.2万股 | $0 | 0股 | +8.2万股 | 新买入 |
| Seven Fleet Capital Management LP |
| 1.62% | — | #8 | $983.5万 | 8.0万股 | $0 | 0股 | +8.0万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | — | #126 | $932.8万 | 7.6万股 | $0 | 0股 | +7.6万股 | 新买入 |
| DV EQUITIES, LLC |
| 1.23% | — | #9 | $860.6万 | 7.0万股 | $0 | 0股 | +7.0万股 | 新买入 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| <0.01% | 0.01% | #102 | $842.5万 | 6.9万股 | $3,017.5万 | 47.8万股 | -40.9万股-85.66% | 减仓 |
