| Bain Capital Life Sciences Investors, LLC |
| 14.74% | 22.93% | #1 | $2.48亿 | 844.8万股 | $2.54亿 | 1,044.8万股 | -200.0万股-19.14% | 减仓 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| 0.04% | 0.05% | #36 | $2.31亿 | 786.4万股 | $2.92亿 | 1,198.2万股 | -411.8万股-34.37% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #102 | $1.53亿 | 519.8万股 | $3,558.5万 | 146.3万股 | +373.5万股+255.38% | 加仓 |
| 富达投资FMR LLC |
| 0.01% | 0.01% | #76 | $1.41亿 | 482.1万股 | $1.31亿 | 539.8万股 | -57.7万股-10.69% | 减仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #83 | $1.05亿 | 358.4万股 | $4,977.8万 | 204.6万股 | +153.8万股+75.20% | 加仓 |
| BAMCO(巴伦基金)BAMCO INC /NY/ |
| 0.14% | 0.28% | #22 | $9,462.5万 | 322.5万股 | $9,312.4万 | 382.8万股 | -60.2万股-15.74% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #111 | $8,077.9万 | 275.3万股 | $4,606.9万 | 189.3万股 | +86.0万股+45.40% | 加仓 |
| 木星资产管理Jupiter Topco LLC |
| 0.03% | — | #41 | $7,098.3万 | 241.9万股 | $0 | 0股 | +241.9万股 | 新买入 |
| 景顺Invesco Ltd. |
| 0.01% | 0.01% | #79 | $6,744.4万 | 229.9万股 | $4,654.5万 | 191.3万股 | +38.6万股+20.16% | 加仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.06% | 0.02% | #31 | $5,050.2万 | 172.1万股 | $1,309.8万 | 53.8万股 | +118.3万股+219.73% | 加仓 |
| 峰会合伙人公共资产SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC |
| 0.87% | 0.58% | #10 | $4,972.1万 | 169.5万股 | $2,170.5万 | 89.2万股 | +80.3万股+89.96% | 加仓 |
| 联博ALLIANCEBERNSTEIN L.P. |
| 0.02% | 0.01% | #52 | $4,681.7万 | 192.4万股 | $3,568.9万 | 122.4万股 | +70.0万股+57.17% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #123 | $4,327.2万 | 146.6万股 | $1,096.2万 | 45.1万股 | +101.5万股+225.36% | 加仓 |
| 瑞银资产管理(美洲)UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| 0.01% | 0.01% | #68 | $4,300.2万 | 146.6万股 | $3,442.3万 | 141.5万股 | +5.1万股+3.59% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #104 | $3,991.8万 | 136.0万股 | $1,318.1万 | 54.2万股 | +81.9万股+151.15% | 加仓 |
| 纽文Nuveen, LLC |
| 0.01% | <0.01% | #59 | $3,970.2万 | 135.3万股 | $56.5万 | 2.3万股 | +133.0万股+5,722.83% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #114 | $3,095.0万 | 105.5万股 | $2,541.8万 | 75.5万股 | +30.0万股+39.69% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #87 | $2,862.1万 | 97.6万股 | $1,044.0万 | 42.9万股 | +54.6万股+127.35% | 加仓 |
| 法国巴黎银行资产管理BNP Paribas Asset Management Holding S.A. |
| 0.03% | — | #43 | $2,732.0万 | 93.1万股 | $0 | 0股 | +93.1万股 | 新买入 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| 0.01% | 0.01% | #61 | $2,707.8万 | 92.3万股 | $2,660.3万 | 109.3万股 | -17.1万股-15.60% | 减仓 |
| 12 West Capital Management LP |
| 4.95% | 2.63% | #2 | $2,647.9万 | 90.3万股 | $1,557.1万 | 64.0万股 | +26.3万股+41.02% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #95 | $2,482.4万 | 84.6万股 | $1,870.3万 | 76.9万股 | +7.7万股+10.07% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | <0.01% | #81 | $2,399.1万 | 81.8万股 | $1,931.1万 | 79.4万股 | +2.4万股+3.02% | 加仓 |
| Champlain Investment 合伙人Champlain Investment Partners, LLC |
| 0.55% | 0.18% | #12 | $2,152.4万 | 73.4万股 | $1,380.5万 | 56.7万股 | +16.6万股+29.29% | 加仓 |
| Voya投资管理VOYA INVESTMENT MANAGEMENT LLC |
| 0.02% | 0.02% | #49 | $2,151.2万 | 73.3万股 | $1,770.4万 | 72.8万股 | +5,516股+0.76% | 加仓 |
| NEXT CENTURY GROWTH INVESTORS LLC |
| 1.04% | 1.17% | #8 | $1,969.9万 | 67.1万股 | $1,588.7万 | 65.3万股 | +1.8万股+2.82% | 加仓 |
| NZS 资本NZS Capital, LLC |
| 0.5% | 0.24% | #13 | $1,924.7万 | 65.6万股 | $705.9万 | 29.0万股 | +36.6万股+126.11% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #89 | $1,909.6万 | 65.1万股 | $148.5万 | 6.1万股 | +59.0万股+966.13% | 加仓 |
| 暮色资产管理EVENTIDE ASSET MANAGEMENT, LLC |
| 0.25% | 0.3% | #17 | $1,868.8万 | 63.7万股 | $1,841.6万 | 75.7万股 | -12.0万股-15.85% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #116 | $1,782.1万 | 60.7万股 | $536.6万 | 22.1万股 | +38.7万股+175.41% | 加仓 |
| Catalio Capital Management, LP |
| 3.21% | 2.05% | #3 | $1,710.7万 | 58.3万股 | $981.9万 | 40.4万股 | +17.9万股+44.47% | 加仓 |
| Rock Springs Capital Management LP |
| 0.82% | 0.82% | #11 | $1,682.6万 | 57.4万股 | $1,392.9万 | 57.3万股 | +1,000股+0.17% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #130 | $1,663.7万 | 56.7万股 | $271.8万 | 11.2万股 | +45.5万股+407.63% | 加仓 |
| 弗雷德·阿尔杰管理FRED ALGER MANAGEMENT, LLC |
| 0.05% | 0.07% | #33 | $1,581.9万 | 53.9万股 | $1,553.0万 | 63.8万股 | -9.9万股-15.53% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #109 | $1,578.2万 | 53.8万股 | $385.2万 | 15.8万股 | +38.0万股+239.72% | 加仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #135 | $1,549.7万 | 44.1万股 | $1,067.0万 | 44.7万股 | -5,748股-1.29% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| 0.01% | <0.01% | #72 | $1,500.8万 | 51.2万股 | $834.1万 | 34.3万股 | +16.9万股+49.22% | 加仓 |
| MFS马萨诸塞金融服务MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
| <0.01% | — | #82 | $1,463.5万 | 49.9万股 | $0 | 0股 | +49.9万股 | 新买入 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.02% | — | #53 | $1,122.8万 | 38.3万股 | $0 | 0股 | +38.3万股 | 新买入 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| 0.03% | 0.02% | #45 | $1,026.9万 | 35.0万股 | $547.4万 | 22.5万股 | +12.5万股+55.56% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #91 | $889.6万 | 30.3万股 | $508.0万 | 20.9万股 | +9.4万股+45.21% | 加仓 |
| Walleye资本Walleye Capital LLC |
| 0.03% | <0.01% | #39 | $876.0万 | 29.9万股 | $47.4万 | 1.9万股 | +27.9万股+1,433.95% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #127 | $872.1万 | 29.7万股 | $362.8万 | 14.9万股 | +14.8万股+99.35% | 加仓 |
| RTW投资RTW INVESTMENTS, LP |
| 0.07% | 0.12% | #27 | $865.5万 | 29.5万股 | $1,204.3万 | 49.5万股 | -20.0万股-40.40% | 减仓 |
| XXEC, Inc. |
| 1.47% | 1.42% | #6 | $813.0万 | 27.9万股 | $813.0万 | 27.9万股 | 00.00% | 持仓不变 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | <0.01% | #142 | $699.1万 | 23.8万股 | $77.9万 | 3.2万股 | +20.6万股+645.17% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #118 | $691.9万 | 23.6万股 | $366.1万 | 15.0万股 | +8.5万股+56.73% | 加仓 |
| 摩羯投资集团Capricorn Investment Group LLC |
| 0.96% | 1.08% | #9 | $648.1万 | 25.7万股 | $648.1万 | 25.7万股 | 00.00% | 持仓不变 |
| LORD, ABBETT & CO. LLC |
| 0.02% | 0.04% | #50 | $588.4万 | 20.1万股 | $1,095.7万 | 45.0万股 | -25.0万股-55.47% | 减仓 |
| Lisanti Capital Growth, LLC |
| 1.22% | 0.76% | #7 | $556.5万 | 19.0万股 | $301.2万 | 12.4万股 | +6.6万股+53.20% | 加仓 |
