| TANG CAPITAL MANAGEMENT LLC |
| 10.05% | 9.2% | #1 | $2.21亿 | 1,304.4万股 | $1.81亿 | 1,223.0万股 | +81.5万股+6.66% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #129 | $1.39亿 | 819.3万股 | $1.16亿 | 784.6万股 | +34.8万股+4.43% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| 0.01% | <0.01% | #81 | $9,536.1万 | 561.9万股 | $2,124.5万 | 143.4万股 | +418.6万股+292.00% | 加仓 |
| NEA Management Company, LLC |
| 4.24% | 3.34% | #2 | $6,736.8万 | 397.0万股 | $5,883.3万 | 397.0万股 | 00.00% | 持仓不变 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.04% | 0.04% | #38 | $5,884.4万 | 346.8万股 | $5,081.3万 | 342.9万股 | +3.9万股+1.13% | 加仓 |
| 箭街资本ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| 0.02% | 0.03% | #53 | $5,539.1万 | 326.4万股 | $4,867.4万 | 328.4万股 | -2.0万股-0.62% | 减仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #153 | $4,394.6万 | 259.0万股 | $3,745.2万 | 252.7万股 | +6.3万股+2.47% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #128 | $3,917.1万 | 230.8万股 | $2,151.2万 | 194.7万股 | +36.1万股+18.57% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| 0.03% | 0.03% | #46 | $3,468.7万 | 204.4万股 | $2,778.2万 | 187.5万股 | +16.9万股+9.04% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #146 | $2,886.5万 | 170.1万股 | $2,276.0万 | 153.6万股 | +16.5万股+10.75% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.04% | 0.04% | #43 | $2,627.0万 | 154.8万股 | $2,465.8万 | 166.4万股 | -11.6万股-6.96% | 减仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.01% | 0.01% | #72 | $2,390.1万 | 140.8万股 | $2,331.2万 | 157.3万股 | -16.5万股-10.46% | 减仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #168 | $2,306.3万 | 135.9万股 | $1,861.9万 | 125.6万股 | +10.3万股+8.17% | 加仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| 0.08% | 0.07% | #29 | $2,089.9万 | 123.2万股 | $1,626.0万 | 109.7万股 | +13.4万股+12.24% | 加仓 |
| Caption管理Caption Management, LLC |
| 0.1% | 0.01% | #25 | $2,077.7万 | 122.4万股 | $147.8万 | 10.0万股 | +112.5万股+1,128.05% | 加仓 |
| 木星资产管理JUPITER ASSET MANAGEMENT LTD |
| 0.09% | 0.06% | #26 | $1,857.3万 | 109.4万股 | $1,190.7万 | 80.3万股 | +29.1万股+36.23% | 加仓 |
| LSV ASSET MANAGEMENT |
| 0.03% | 0.03% | #44 | $1,831.8万 | 107.9万股 | $1,540.7万 | 104.0万股 | +4.0万股+3.84% | 加仓 |
| 野村控股NOMURA HOLDINGS INC |
| 0.02% | 0.04% | #61 | $1,660.7万 | 97.9万股 | $1,435.9万 | 96.9万股 | +9,692股+1.00% | 加仓 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| 0.01% | 0.01% | #89 | $1,610.0万 | 94.9万股 | $1,406.1万 | 94.9万股 | -59股-0.01% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #144 | $1,465.5万 | 86.4万股 | $1,221.3万 | 82.4万股 | +3.9万股+4.79% | 加仓 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #110 | $1,379.5万 | 81.3万股 | $968.4万 | 65.3万股 | +15.9万股+24.41% | 加仓 |
| 木星资产管理Jupiter Topco LLC |
| <0.01% | — | #103 | $1,021.9万 | 60.2万股 | $0 | 0股 | +60.2万股 | 新买入 |
| DZ 银行 AG Deutsche Zentral Genossenschafts 银行 Frankfurt am MainDZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main |
| 0.01% | 0.01% | #85 | $1,012.5万 | 59.7万股 | $911.6万 | 61.5万股 | -1.8万股-3.00% | 减仓 |
| 保德信金融PRUDENTIAL FINANCIAL INC |
| 0.01% | 0.01% | #73 | $988.2万 | 58.2万股 | $875.3万 | 59.1万股 | -8,265股-1.40% | 减仓 |
| O'Shaughnessy资产管理O'SHAUGHNESSY ASSET MANAGEMENT, LLC |
| 0.04% | 0.03% | #36 | $963.0万 | 56.7万股 | $613.6万 | 41.4万股 | +15.3万股+37.07% | 加仓 |
| Hillsdale Investment Management Inc. |
| 0.21% | 0.08% | #14 | $934.9万 | 55.1万股 | $311.1万 | 21.0万股 | +34.1万股+162.46% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| 0.01% | 0.02% | #86 | $814.5万 | 48.0万股 | $1,379.2万 | 93.1万股 | -45.1万股-48.43% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #176 | $789.4万 | 46.5万股 | $602.7万 | 40.7万股 | +5.9万股+14.39% | 加仓 |
| Woodline合伙人Woodline Partners LP |
| 0.02% | 0.03% | #55 | $774.3万 | 45.6万股 | $676.2万 | 45.6万股 | 00.00% | 持仓不变 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #171 | $756.8万 | 44.6万股 | $684.5万 | 46.2万股 | -1.6万股-3.44% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | 0.01% | #108 | $741.7万 | 43.7万股 | $1,109.7万 | 74.9万股 | -31.2万股-41.63% | 减仓 |
| RICE HALL JAMES & ASSOCIATES, LLC |
| 0.34% | 0.4% | #8 | $707.0万 | 41.7万股 | $723.1万 | 48.8万股 | -7.1万股-14.61% | 减仓 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #160 | $698.9万 | 41.2万股 | $407.8万 | 27.5万股 | +13.7万股+49.67% | 加仓 |
| Connor Clark & Lunn投资管理Connor, Clark & Lunn Investment Management Ltd. |
| 0.01% | 0.01% | #67 | $693.1万 | 40.8万股 | $586.0万 | 39.5万股 | +1.3万股+3.30% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #204 | $641.5万 | 37.8万股 | $375.4万 | 25.3万股 | +12.5万股+49.22% | 加仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #234 | $632.1万 | 37.2万股 | $472.4万 | 31.9万股 | +5.4万股+16.85% | 加仓 |
| 里霍尔茨财富管理RITHOLTZ WEALTH MANAGEMENT |
| 0.09% | 0.08% | #27 | $616.1万 | 36.3万股 | $466.0万 | 31.4万股 | +4.9万股+15.47% | 加仓 |
| Voloridge投资管理VOLORIDGE INVESTMENT MANAGEMENT, LLC |
| 0.03% | 0.03% | #48 | $615.0万 | 36.2万股 | $782.8万 | 52.8万股 | -16.6万股-31.38% | 减仓 |
| IFP顾问IFP Advisors, Inc |
| 0.11% | 0.1% | #23 | $613.7万 | 36.2万股 | $485.8万 | 32.8万股 | +3.4万股+10.32% | 加仓 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #114 | $603.4万 | 35.6万股 | $541.3万 | 36.5万股 | -9,664股-2.65% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #173 | $595.4万 | 35.1万股 | $497.6万 | 33.6万股 | +1.5万股+4.49% | 加仓 |
| Norris Financial Group, LLC |
| 2.31% | 1.66% | #3 | $580.9万 | 34.2万股 | $507.6万 | 34.2万股 | -146股-0.04% | 减仓 |
| SquarepointSquarepoint Ops LLC |
| 0.01% | 0.01% | #88 | $538.7万 | 31.7万股 | $473.9万 | 32.0万股 | -2,374股-0.74% | 减仓 |
| 雷蒙德詹姆斯金融RAYMOND JAMES FINANCIAL INC |
| <0.01% | <0.01% | #149 | $527.0万 | 31.1万股 | $393.9万 | 26.6万股 | +4.5万股+16.86% | 加仓 |
| 北欧投资管理NORDEA INVESTMENT MANAGEMENT AB |
| <0.01% | <0.01% | #104 | $504.9万 | 29.6万股 | $415.8万 | 29.2万股 | +4,000股+1.37% | 加仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #235 | $497.6万 | 29.1万股 | $452.5万 | 32.4万股 | -3.2万股-9.99% | 减仓 |
| PDT Partners, LLC |
| 0.24% | 0.23% | #13 | $450.5万 | 26.5万股 | $393.5万 | 26.5万股 | 00.00% | 持仓不变 |
| 西格尔·布莱恩特·哈米尔SEGALL BRYANT & HAMILL, LLC |
| 0.05% | 0.03% | #33 | $447.6万 | 26.4万股 | $216.8万 | 14.6万股 | +11.7万股+80.30% | 加仓 |
| NAVELLIER & ASSOCIATES INC |
| 0.35% | 0.18% | #7 | $436.4万 | 25.7万股 | $170.3万 | 11.5万股 | +14.2万股+123.73% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #151 | $414.6万 | 24.4万股 | $173.6万 | 11.7万股 | +12.7万股+108.50% | 加仓 |
