| Corvex 管理Corvex Management LP |
| 10.03% | 8.24% | #3 | $3.28亿 | 478.5万股 | $2.07亿 | 322.8万股 | +155.6万股+48.21% | 加仓 |
| Casdin Capital, LLC |
| 12.74% | 14.62% | #1 | $2.54亿 | 370.7万股 | $1.93亿 | 300.7万股 | +70.0万股+23.28% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #123 | $1.17亿 | 170.6万股 | $9,958.6万 | 155.1万股 | +15.6万股+10.03% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| 0.01% | 0.01% | #75 | $1.15亿 | 166.9万股 | $8,573.2万 | 133.5万股 | +33.4万股+25.05% | 加仓 |
| ARK投资管理ARK Investment Management LLC |
| 0.72% | 0.66% | #15 | $1.11亿 | 161.0万股 | $8,506.5万 | 132.5万股 | +28.6万股+21.56% | 加仓 |
| 威廉·布莱尔投资管理WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
| 0.29% | 0.16% | #23 | $9,615.5万 | 140.1万股 | $4,978.8万 | 77.5万股 | +62.5万股+80.67% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| 0.01% | 0.01% | #76 | $7,180.5万 | 104.6万股 | $4,932.1万 | 76.8万股 | +27.8万股+36.19% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #93 | $6,784.7万 | 98.8万股 | $5,040.2万 | 46.8万股 | +52.0万股+111.26% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #131 | $6,034.4万 | 87.9万股 | $5,513.8万 | 85.9万股 | +2.0万股+2.38% | 加仓 |
| First Light Asset Management, LLC |
| 3.27% | 1.4% | #7 | $5,381.6万 | 78.4万股 | $1,560.1万 | 24.3万股 | +54.1万股+222.70% | 加仓 |
| 深轨资本Deep Track Capital, LP |
| 0.7% | — | #16 | $4,805.5万 | 70.0万股 | $0 | 0股 | +70.0万股 | 新买入 |
| 三井住友信托集团Sumitomo Mitsui Trust Group, Inc. |
| 0.03% | 0.03% | #55 | $4,576.1万 | 66.7万股 | $4,068.1万 | 63.3万股 | +3.3万股+5.23% | 加仓 |
| Amova资产管理Amova Asset Management Americas, Inc. |
| 0.59% | 0.58% | #17 | $4,570.1万 | 66.7万股 | $4,102.4万 | 63.9万股 | +2.8万股+4.35% | 加仓 |
| Zweig-DiMenna Associates LLC |
| 3.56% | 6.13% | #6 | $3,926.4万 | 57.2万股 | $4,426.6万 | 68.9万股 | -11.7万股-17.02% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #117 | $3,791.1万 | 55.2万股 | $3,527.3万 | 54.9万股 | +2,978股+0.54% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #136 | $3,623.5万 | 52.8万股 | $3,034.0万 | 47.2万股 | +5.5万股+11.72% | 加仓 |
| GAGNON SECURITIES LLC |
| 7.01% | 4.49% | #5 | $3,603.2万 | 52.5万股 | $1,946.8万 | 30.3万股 | +22.2万股+73.14% | 加仓 |
| 安本标准投资Aberdeen Group plc |
| 0.04% | 0.02% | #48 | $3,138.7万 | 45.7万股 | $1,477.7万 | 23.0万股 | +22.7万股+98.70% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #110 | $3,056.4万 | 44.5万股 | $2,235.5万 | 34.8万股 | +9.7万股+27.90% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #115 | $2,612.1万 | 38.0万股 | $418.1万 | 6.5万股 | +31.5万股+484.47% | 加仓 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| <0.01% | <0.01% | #85 | $2,388.5万 | 34.8万股 | $2,189.9万 | 34.1万股 | +6,922股+2.03% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #125 | $2,376.7万 | 34.6万股 | $1,506.6万 | 23.5万股 | +11.2万股+47.57% | 加仓 |
| Assenagon资产管理Assenagon Asset Management S.A. |
| 0.03% | 0.01% | #56 | $2,083.1万 | 30.3万股 | $610.9万 | 9.5万股 | +20.8万股+218.97% | 加仓 |
| Caption管理Caption Management, LLC |
| 0.09% | 0.03% | #34 | $1,986.7万 | 28.9万股 | $446.3万 | 7.0万股 | +22.0万股+316.40% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | 0.01% | #88 | $1,928.6万 | 28.1万股 | $3,899.6万 | 60.7万股 | -32.6万股-53.73% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #95 | $1,926.5万 | 28.1万股 | $1,706.2万 | 26.6万股 | +1.5万股+5.58% | 加仓 |
| 挪威央行投资管理NORGES BANK |
| <0.01% | <0.01% | #120 | $1,874.8万 | 27.3万股 | $602.2万 | 6.8万股 | +20.5万股+301.62% | 加仓 |
| 暮色资产管理EVENTIDE ASSET MANAGEMENT, LLC |
| 0.25% | 0.49% | #24 | $1,850.6万 | 27.0万股 | $2,946.8万 | 45.9万股 | -18.9万股-41.28% | 减仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #121 | $1,432.5万 | 20.9万股 | $326.4万 | 5.1万股 | +15.8万股+310.55% | 加仓 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | <0.01% | #105 | $1,425.6万 | 20.8万股 | $1,258.0万 | 19.6万股 | +1.2万股+6.01% | 加仓 |
| Portolan 资本管理Portolan Capital Management, LLC |
| 0.51% | 0.35% | #19 | $1,375.2万 | 20.0万股 | $658.7万 | 10.3万股 | +9.8万股+95.29% | 加仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.02% | 0.01% | #66 | $1,373.7万 | 20.0万股 | $531.1万 | 8.3万股 | +11.7万股+141.97% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #152 | $1,356.4万 | 19.8万股 | $1,113.5万 | 17.3万股 | +2.4万股+13.95% | 加仓 |
| Alamea Verwaltungs GmbH |
| 10.2% | 8.85% | #2 | $1,276.8万 | 18.6万股 | $1,194.4万 | 18.6万股 | 00.00% | 持仓不变 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #126 | $1,262.1万 | 18.4万股 | $1,128.8万 | 17.6万股 | +8,074股+4.59% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #124 | $1,221.5万 | 17.8万股 | $1,095.7万 | 17.1万股 | +7,322股+4.29% | 加仓 |
| Gagnon Advisors, LLC |
| 7.76% | 7% | #4 | $1,221.1万 | 17.8万股 | $951.9万 | 14.8万股 | +3.0万股+20.00% | 加仓 |
| ASHFORD CAPITAL MANAGEMENT INC |
| 1.33% | 1.38% | #10 | $1,120.7万 | 17.5万股 | $1,120.7万 | 17.5万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #91 | $1,068.0万 | 15.6万股 | $962.7万 | 15.0万股 | +5,669股+3.78% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #112 | $1,049.4万 | 15.3万股 | $927.7万 | 14.4万股 | +8,408股+5.82% | 加仓 |
| 洛克菲勒资本管理Rockefeller Capital Management L.P. |
| 0.02% | 0.01% | #65 | $1,037.7万 | 15.1万股 | $620.3万 | 9.7万股 | +5.5万股+56.50% | 加仓 |
| 安大略医疗养老基金(HOOPP)HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND |
| 0.01% | — | #67 | $971.4万 | 14.2万股 | $0 | 0股 | +14.2万股 | 新买入 |
| 都铎投资TUDOR INVESTMENT CORP ET AL |
| 0.01% | 0.01% | #69 | $852.9万 | 12.4万股 | $331.6万 | 5.2万股 | +7.3万股+140.59% | 加仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #87 | $849.1万 | 12.4万股 | $49.6万 | 7,718股 | +11.6万股+1,502.62% | 加仓 |
| 雷蒙德詹姆斯金融RAYMOND JAMES FINANCIAL INC |
| <0.01% | 0.01% | #114 | $847.3万 | 12.3万股 | $3,876.9万 | 61.0万股 | -48.7万股-79.77% | 减仓 |
| SILVERARC CAPITAL MANAGEMENT, LLC |
| 0.87% | — | #13 | $839.4万 | 12.2万股 | $0 | 0股 | +12.2万股 | 新买入 |
| Royce联营ROYCE & ASSOCIATES LP |
| 0.06% | 0.09% | #43 | $769.8万 | 11.2万股 | $902.4万 | 14.1万股 | -2.8万股-20.20% | 减仓 |
| 弗雷德·阿尔杰管理FRED ALGER MANAGEMENT, LLC |
| 0.02% | 0.06% | #57 | $745.0万 | 10.9万股 | $1,302.2万 | 20.3万股 | -9.4万股-46.48% | 减仓 |
| Science & Technology Partners, L.P. |
| 1.23% | 4.05% | #11 | $730.3万 | 10.6万股 | $1,549.0万 | 24.1万股 | -13.5万股-55.89% | 减仓 |
| THRIVENT FINANCIAL FOR LUTHERANS |
| 0.01% | 0.02% | #73 | $700.2万 | 10.2万股 | $987.2万 | 15.4万股 | -5.2万股-33.65% | 减仓 |
