| 贝莱德BlackRock, Inc. |
| 0.01% | 0.01% | #116 | $4.35亿 | 935.0万股 | $4.55亿 | 879.7万股 | +55.3万股+6.28% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| 0.06% | 0.07% | #54 | $1.79亿 | 385.3万股 | $1.71亿 | 331.6万股 | +53.7万股+16.20% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.01% | 0.01% | #111 | $1.54亿 | 330.5万股 | $1.67亿 | 323.9万股 | +6.7万股+2.06% | 加仓 |
| 停战资本ARMISTICE CAPITAL, LLC |
| 1.51% | 1.74% | #6 | $1.23亿 | 264.6万股 | $9,797.0万 | 189.5万股 | +75.1万股+39.62% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #174 | $1.17亿 | 251.7万股 | $1.28亿 | 246.7万股 | +5.0万股+2.01% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #147 | $1.14亿 | 246.0万股 | $1.18亿 | 228.8万股 | +17.2万股+7.50% | 加仓 |
| 野村资产管理国际NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| 0.17% | 0.18% | #23 | $1.11亿 | 237.8万股 | $1.05亿 | 203.7万股 | +34.1万股+16.74% | 加仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| 0.02% | 0.02% | #79 | $9,665.4万 | 207.8万股 | $1.19亿 | 230.7万股 | -22.9万股-9.92% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | 0.01% | #141 | $7,303.9万 | 157.0万股 | $8,393.4万 | 162.4万股 | -5.3万股-3.29% | 减仓 |
| 斯蒂芬斯投资管理Stephens Investment Management Group LLC |
| 0.74% | 0.96% | #12 | $6,910.6万 | 148.6万股 | $6,985.0万 | 135.1万股 | +13.4万股+9.95% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.09% | 0.14% | #37 | $6,875.0万 | 147.8万股 | $8,814.3万 | 170.5万股 | -22.7万股-13.31% | 减仓 |
| 卢米斯塞勒斯LOOMIS SAYLES & CO L P |
| 0.09% | 0.1% | #43 | $6,861.1万 | 147.5万股 | $7,369.9万 | 142.6万股 | +4.9万股+3.47% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| 0.01% | 0.01% | #106 | $6,602.0万 | 141.9万股 | $7,898.5万 | 152.8万股 | -10.9万股-7.10% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.04% | 0.01% | #61 | $5,508.5万 | 118.4万股 | $1,402.0万 | 27.1万股 | +91.3万股+336.67% | 加仓 |
| GW&K Investment Management, LLC |
| 0.38% | 0.48% | #18 | $4,824.2万 | 103.7万股 | $5,454.2万 | 105.5万股 | -1.8万股-1.70% | 减仓 |
| Sofinnova Investments, Inc. |
| 2.49% | 1.87% | #3 | $4,820.0万 | 103.6万股 | $4,932.8万 | 95.4万股 | +8.2万股+8.59% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| 0.04% | 0.03% | #62 | $4,289.0万 | 92.2万股 | $2,575.2万 | 49.8万股 | +42.4万股+85.10% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #177 | $4,078.2万 | 87.7万股 | $3,609.7万 | 75.5万股 | +12.2万股+16.09% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | 0.01% | #148 | $3,811.2万 | 81.9万股 | $4,427.2万 | 85.6万股 | -3.7万股-4.33% | 减仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.02% | 0.02% | #80 | $3,570.4万 | 76.8万股 | $3,217.4万 | 62.2万股 | +14.5万股+23.33% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #139 | $3,410.9万 | 73.3万股 | $3,615.5万 | 69.9万股 | +3.4万股+4.85% | 加仓 |
| ASHFORD CAPITAL MANAGEMENT INC |
| 3.95% | 4.12% | #2 | $3,336.0万 | 64.5万股 | $3,336.0万 | 64.5万股 | 00.00% | 持仓不变 |
| Woodline合伙人Woodline Partners LP |
| 0.1% | 0.09% | #34 | $3,294.2万 | 70.8万股 | $2,320.9万 | 44.9万股 | +25.9万股+57.75% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | 0.01% | #130 | $3,272.2万 | 70.4万股 | $3,649.2万 | 70.6万股 | -2,424股-0.34% | 减仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #181 | $2,888.7万 | 62.1万股 | $3,691.8万 | 71.4万股 | -9.3万股-13.04% | 减仓 |
| Soleus 资本管理Soleus Capital Management, L.P. |
| 0.83% | — | #9 | $2,418.5万 | 52.0万股 | $0 | 0股 | +52.0万股 | 新买入 |
| RICE HALL JAMES & ASSOCIATES, LLC |
| 1.11% | 1.37% | #8 | $2,280.0万 | 49.0万股 | $2,467.8万 | 47.7万股 | +1.3万股+2.68% | 加仓 |
| 系统金融管理SYSTEMATIC FINANCIAL MANAGEMENT LP |
| 0.44% | 0.45% | #16 | $2,205.2万 | 47.4万股 | $1,944.0万 | 37.6万股 | +9.8万股+26.07% | 加仓 |
| 安本标准投资Aberdeen Group plc |
| 0.03% | 0.02% | #70 | $2,107.9万 | 45.3万股 | $1,424.4万 | 27.6万股 | +17.8万股+64.47% | 加仓 |
| 百达资产管理Pictet Asset Management Holding SA |
| 0.02% | 0.02% | #77 | $2,023.7万 | 43.2万股 | $2,226.9万 | 45.1万股 | -1.8万股-4.06% | 减仓 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #194 | $1,837.6万 | 39.5万股 | $2,133.2万 | 41.3万股 | -1.8万股-4.26% | 减仓 |
| 胜利资本管理VICTORY CAPITAL MANAGEMENT INC |
| 0.01% | 0.02% | #96 | $1,818.9万 | 39.1万股 | $2,596.9万 | 50.2万股 | -11.1万股-22.16% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #140 | $1,789.8万 | 38.5万股 | $1,908.6万 | 36.9万股 | +1.6万股+4.22% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #163 | $1,755.3万 | 37.7万股 | $1,873.3万 | 36.2万股 | +1.5万股+4.14% | 加仓 |
| 施罗德投资管理SCHRODER INVESTMENT MANAGEMENT GROUP |
| 0.01% | 0.01% | #89 | $1,722.3万 | 36.8万股 | $868.9万 | 17.6万股 | +19.2万股+109.01% | 加仓 |
| 信安金融集团PRINCIPAL FINANCIAL GROUP INC |
| 0.01% | 0.01% | #104 | $1,620.7万 | 34.8万股 | $1,763.2万 | 34.1万股 | +7,344股+2.15% | 加仓 |
| Freestone Grove合伙人Freestone Grove Partners LP |
| 0.09% | 0.23% | #38 | $1,471.6万 | 31.6万股 | $3,315.0万 | 64.1万股 | -32.5万股-50.66% | 减仓 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #230 | $1,437.6万 | 30.9万股 | $1,082.2万 | 20.9万股 | +10.0万股+47.63% | 加仓 |
| Krensavage Asset Management, LLC |
| 4.96% | 5.67% | #1 | $1,305.4万 | 28.1万股 | $1,450.8万 | 28.1万股 | 00.00% | 持仓不变 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #224 | $1,286.1万 | 27.2万股 | $1,237.4万 | 25.1万股 | +2.2万股+8.61% | 加仓 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #161 | $1,221.7万 | 26.3万股 | $1,116.7万 | 21.6万股 | +4.7万股+21.58% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #200 | $1,025.3万 | 22.0万股 | $1,081.0万 | 20.9万股 | +1.1万股+5.42% | 加仓 |
| 格伦米德信托GLENMEDE TRUST CO NA |
| 0.04% | 0.06% | #60 | $981.1万 | 21.1万股 | $1,132.5万 | 21.9万股 | -8,147股-3.72% | 减仓 |
| 加拿大公共部门养老金投资委员会(PSP)PUBLIC SECTOR PENSION INVESTMENT BOARD |
| 0.02% | 0.03% | #74 | $927.2万 | 19.9万股 | $1,060.5万 | 20.5万股 | -5,807股-2.83% | 减仓 |
| Mutual of America资本管理MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC |
| 0.08% | — | #47 | $850.7万 | 18.3万股 | $0 | 0股 | +18.3万股 | 新买入 |
| 阿默普莱斯金融AMERIPRISE FINANCIAL INC |
| <0.01% | <0.01% | #189 | $797.8万 | 17.2万股 | $898.9万 | 17.4万股 | -2,376股-1.37% | 减仓 |
| Aristotle Capital Boston, LLC |
| 0.53% | 0.65% | #15 | $789.2万 | 17.0万股 | $1,050.5万 | 20.3万股 | -3.3万股-16.45% | 减仓 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #150 | $744.8万 | 16.0万股 | $832.3万 | 16.1万股 | -896股-0.56% | 减仓 |
| 英仕曼集团Man Group plc |
| 0.01% | 0.01% | #91 | $727.5万 | 15.6万股 | $387.6万 | 7.5万股 | +8.1万股+108.58% | 加仓 |
| THIRD AVENUE MANAGEMENT LLC |
| 1.14% | 1.28% | #7 | $710.3万 | 15.3万股 | $789.4万 | 15.3万股 | 00.00% | 持仓不变 |
