| BVF INC/IL |
| 1.21% | 1.74% | #1 | $4,717.7万 | 1,982.2万股 | $5,451.2万 | 1,982.2万股 | 00.00% | 持仓不变 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #14 | $239.0万 | 100.4万股 | $276.2万 | 100.4万股 | -243股-0.02% | 减仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #4 | $200.0万 | 84.0万股 | $171.7万 | 62.4万股 | +21.6万股+34.56% | 加仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #10 | $184.1万 | 77.4万股 | $218.0万 | 79.3万股 | -1.9万股-2.40% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #29 | $123.6万 | 51.9万股 | $144.2万 | 52.4万股 | -5,004股-0.95% | 减仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #20 | $81.2万 | 34.0万股 | $107.1万 | 39.0万股 | -5.0万股-12.84% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #22 | $60.3万 | 25.3万股 | $82.0万 | 29.8万股 | -4.5万股-15.03% | 减仓 |
| 箭街资本ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | <0.01% | #16 | $55.4万 | 23.3万股 | $111.6万 | 40.6万股 | -17.3万股-42.57% | 减仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #27 | $37.9万 | 15.9万股 | $43.4万 | 15.8万股 | +1,307股+0.83% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #30 | $31.4万 | 13.2万股 | $26.6万 | 9.2万股 | +4.0万股+43.23% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #19 | $24.5万 | 10.3万股 | $10.8万 | 3.9万股 | +6.4万股+163.04% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | — | #18 | $22.0万 | 9.2万股 | $0 | 0股 | +9.2万股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #28 | $20.4万 | 8.6万股 | $27.9万 | 10.2万股 | -1.6万股-15.76% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #34 | $14.7万 | 6.2万股 | $17.5万 | 6.4万股 | -1,747股-2.75% | 减仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #25 | $7.3万 | 3.1万股 | $1.8万 | 6,620股 | +2.4万股+365.26% | 加仓 |
| 跳跃金融Jump Financial, LLC |
| <0.01% | <0.01% | #11 | $5.7万 | 2.4万股 | $3.1万 | 1.1万股 | +1.3万股+116.31% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #35 | $4.6万 | 1.9万股 | $15.9万 | 5.8万股 | -3.8万股-66.25% | 减仓 |
| Verdad Advisers, LP |
| 0.04% | — | #2 | $3.9万 | 1.6万股 | $0 | 0股 | +1.6万股 | 新买入 |
| China Universal Asset Management Co., Ltd. |
| <0.01% | <0.01% | #6 | $3.9万 | 1.6万股 | $4.9万 | 1.8万股 | -1,655股-9.27% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #40 | $3.5万 | 1.4万股 | $5.9万 | 2.2万股 | -7,135股-32.98% | 减仓 |
| 正交资本Quadrature Capital Ltd |
| <0.01% | — | #15 | $3.1万 | 1.3万股 | $0 | 0股 | +1.3万股 | 新买入 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #26 | $2.6万 | 1.1万股 | $49.5万 | 18.0万股 | -16.9万股-93.89% | 减仓 |
| AXQ CAPITAL, LP |
| <0.01% | — | #5 | $2.5万 | 1.0万股 | $0 | 0股 | +1.0万股 | 新买入 |
| SG Americas Securities, LLC |
| <0.01% | — | #32 | $2.5万 | 1.0万股 | $0 | 0股 | +1.0万股 | 新买入 |
| Quinn Opportunity Partners LLC |
| <0.01% | <0.01% | #8 | $2.4万 | 1.0万股 | $2.8万 | 1.0万股 | 00.00% | 持仓不变 |
| Silverberg Bernstein Capital Management LLC |
| 0.01% | 0.02% | #3 | $2.4万 | 1.0万股 | $2.8万 | 1.0万股 | 00.00% | 持仓不变 |
| EFG国际EFG International AG |
| <0.01% | <0.01% | #13 | $2.4万 | 9,900股 | $2.7万 | 9,900股 | 00.00% | 持仓不变 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #42 | $2.1万 | 7,798股 | $2.0万 | 7,640股 | +158股+2.07% | 加仓 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #37 | $1.7万 | 7,278股 | $1.6万 | 5,791股 | +1,487股+25.68% | 加仓 |
| Banque Cantonale Vaudoise |
| <0.01% | <0.01% | #9 | $1.7万 | 7,021股 | $1.9万 | 7,021股 | 00.00% | 持仓不变 |
| 未来资产环球投资Mirae Asset Global Investments Co., Ltd. |
| <0.01% | <0.01% | #31 | $1.1万 | 4,552股 | $1.4万 | 5,247股 | -695股-13.25% | 减仓 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #17 | $9,760 | 4,101股 | $1.9万 | 7,009股 | -2,908股-41.49% | 减仓 |
| 花旗集团CITIGROUP INC |
| <0.01% | <0.01% | #38 | $9,549 | 4,012股 | $7,730 | 2,811股 | +1,201股+42.73% | 加仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #39 | $6,424 | 2,699股 | $6,628 | 2,410股 | +289股+11.99% | 加仓 |
| 广发基金管理GF FUND MANAGEMENT CO. LTD. |
| <0.01% | <0.01% | #24 | $4,960 | 2,084股 | $6,166 | 2,242股 | -158股-7.05% | 减仓 |
| Forum Finance Group S.A. |
| <0.01% | <0.01% | #7 | $4,760 | 2,000股 | $5,500 | 2,000股 | 00.00% | 持仓不变 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #45 | $3,000 | 1,289股 | $2,000 | 760股 | +529股+69.61% | 加仓 |
| SBI Securities Co., Ltd. |
| <0.01% | — | #23 | $2,849 | 1,197股 | $0 | 0股 | +1,197股 | 新买入 |
| PNC金融服务集团PNC FINANCIAL SERVICES GROUP, INC. |
| <0.01% | <0.01% | #41 | $2,380 | 1,000股 | $2,750 | 1,000股 | 00.00% | 持仓不变 |
| 洛克菲勒资本管理Rockefeller Capital Management L.P. |
| <0.01% | <0.01% | #36 | $2,380 | 1,000股 | $2,750 | 1,000股 | 00.00% | 持仓不变 |
| Activest Wealth Management |
| <0.01% | <0.01% | #12 | $2,380 | 1,000股 | $2,750 | 1,000股 | 00.00% | 持仓不变 |
| OSAIC控股OSAIC HOLDINGS, INC. |
| <0.01% | <0.01% | #44 | $523 | 220股 | $607 | 221股 | -1股-0.45% | 减仓 |
| Strengthening Families & Communities, LLC |
| <0.01% | <0.01% | #21 | $476 | 200股 | $550 | 200股 | 00.00% | 持仓不变 |
| Farther金融顾问Farther Finance Advisors, LLC |
| <0.01% | <0.01% | #43 | $102 | 43股 | $120 | 43股 | 00.00% | 持仓不变 |
| Caitong International Asset Management Co., Ltd |
| <0.01% | <0.01% | #33 | $83 | 35股 | $8 | 3股 | +32股+1,066.67% | 加仓 |
