| 木星资产管理Jupiter Topco LLC |
| 0.26% | — | #39 | $6.43亿 | 1,132.4万股 | $0 | 0股 | +1,132.4万股 | 新买入 |
| 贝莱德BlackRock, Inc. |
| 0.01% | <0.01% | #155 | $4.56亿 | 802.1万股 | $2.32亿 | 779.2万股 | +22.9万股+2.93% | 加仓 |
| 富达投资FMR LLC |
| 0.02% | 0.02% | #108 | $4.03亿 | 709.7万股 | $3.26亿 | 1,096.8万股 | -387.1万股-35.30% | 减仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| 0.02% | <0.01% | #111 | $2.60亿 | 456.8万股 | $3,996.3万 | 134.5万股 | +322.3万股+239.63% | 加仓 |
| 道富集团STATE STREET CORP |
| 0.01% | 0.01% | #153 | $2.42亿 | 425.6万股 | $1.47亿 | 496.0万股 | -70.4万股-14.19% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #168 | $2.33亿 | 410.9万股 | $1.20亿 | 404.6万股 | +6.3万股+1.55% | 加仓 |
| 洞察顾问PERCEPTIVE ADVISORS LLC |
| 3.2% | 2.4% | #9 | $2.13亿 | 375.3万股 | $1.23亿 | 414.3万股 | -39.0万股-9.41% | 减仓 |
| 野村资产管理国际NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| 0.24% | 0.17% | #41 | $1.60亿 | 281.3万股 | $9,716.7万 | 327.1万股 | -45.8万股-14.00% | 减仓 |
| Adage资本合伙人ADAGE CAPITAL PARTNERS GP, L.L.C. |
| 0.2% | 0.04% | #43 | $1.46亿 | 256.9万股 | $2,902.7万 | 97.7万股 | +159.2万股+162.98% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| 0.01% | <0.01% | #152 | $1.35亿 | 237.2万股 | $7,041.1万 | 237.0万股 | +2,328股+0.10% | 加仓 |
| Rock Springs Capital Management LP |
| 6.04% | 2.59% | #2 | $1.24亿 | 217.9万股 | $4,391.0万 | 147.8万股 | +70.1万股+47.44% | 加仓 |
| 停战资本ARMISTICE CAPITAL, LLC |
| 1.44% | 2.59% | #16 | $1.18亿 | 207.3万股 | $1.46亿 | 489.7万股 | -282.5万股-57.68% | 减仓 |
| Kynam Capital Management, LP |
| 6.28% | 4.44% | #1 | $1.14亿 | 200.0万股 | $7,201.5万 | 242.4万股 | -42.4万股-17.49% | 减仓 |
| 斯蒂芬斯投资管理Stephens Investment Management Group LLC |
| 1.14% | 0.73% | #18 | $1.07亿 | 187.5万股 | $5,343.2万 | 179.8万股 | +7.7万股+4.27% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| 0.14% | 0.09% | #49 | $1.04亿 | 183.3万股 | $5,843.3万 | 196.7万股 | -13.4万股-6.80% | 减仓 |
| EMERALD ADVISERS, LLC |
| 2.14% | 1.46% | #11 | $9,094.6万 | 160.1万股 | $4,626.4万 | 155.7万股 | +4.4万股+2.81% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.06% | 0.04% | #62 | $8,894.5万 | 156.6万股 | $4,481.0万 | 150.8万股 | +5.7万股+3.81% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #176 | $8,757.9万 | 154.2万股 | $5,077.9万 | 170.9万股 | -16.8万股-9.80% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| 0.01% | 0.01% | #149 | $8,722.2万 | 153.5万股 | $5,109.3万 | 172.0万股 | -18.4万股-10.72% | 减仓 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| 0.01% | 0.01% | #113 | $8,709.4万 | 153.3万股 | $3,037.2万 | 102.2万股 | +51.1万股+49.97% | 加仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| 0.08% | 0.02% | #59 | $8,199.0万 | 144.3万股 | $1,988.1万 | 66.9万股 | +77.4万股+115.68% | 加仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.04% | 0.01% | #80 | $8,183.3万 | 144.0万股 | $2,485.4万 | 83.7万股 | +60.4万股+72.19% | 加仓 |
| Driehaus资本管理DRIEHAUS CAPITAL MANAGEMENT LLC |
| 0.47% | 0.28% | #31 | $8,175.7万 | 143.9万股 | $3,810.4万 | 128.3万股 | +15.7万股+12.21% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| 0.01% | <0.01% | #157 | $7,670.5万 | 135.0万股 | $1,611.4万 | 54.2万股 | +80.8万股+148.94% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| 0.06% | 0.01% | #64 | $7,573.9万 | 133.3万股 | $530.4万 | 17.9万股 | +115.5万股+646.74% | 加仓 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| 0.01% | <0.01% | #150 | $7,491.1万 | 131.9万股 | $1,202.8万 | 40.5万股 | +91.4万股+225.74% | 加仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| 0.03% | <0.01% | #89 | $6,572.7万 | 115.7万股 | $325.0万 | 10.9万股 | +104.8万股+957.72% | 加仓 |
| MPM BioImpact LLC |
| 3.89% | 2.6% | #6 | $6,378.2万 | 112.3万股 | $3,367.2万 | 113.3万股 | -1.1万股-0.94% | 减仓 |
| 纽文Nuveen, LLC |
| 0.01% | 0.01% | #117 | $5,991.4万 | 105.5万股 | $2,788.5万 | 93.9万股 | +11.6万股+12.37% | 加仓 |
| EMERALD MUTUAL FUND ADVISERS 信托EMERALD MUTUAL FUND ADVISERS TRUST |
| 2.06% | 1.36% | #12 | $5,862.9万 | 103.2万股 | $2,807.7万 | 94.5万股 | +8.7万股+9.21% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #177 | $5,019.9万 | 88.4万股 | $3,249.9万 | 109.4万股 | -21.0万股-19.22% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| 0.01% | <0.01% | #162 | $4,970.9万 | 87.5万股 | $2,321.6万 | 78.1万股 | +9.4万股+11.98% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.01% | <0.01% | #158 | $4,699.8万 | 82.7万股 | $2,349.5万 | 79.1万股 | +3.6万股+4.61% | 加仓 |
| Eversept Partners, LP |
| 2.35% | 0.85% | #10 | $4,539.0万 | 79.9万股 | $1,612.1万 | 54.3万股 | +25.6万股+47.25% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| 0.01% | <0.01% | #140 | $3,759.8万 | 66.2万股 | $1,820.1万 | 61.3万股 | +4.9万股+8.03% | 加仓 |
| Ensign Peak顾问Ensign Peak Advisors, Inc |
| 0.06% | 0.04% | #67 | $3,362.1万 | 59.2万股 | $2,126.4万 | 71.6万股 | -12.4万股-17.31% | 减仓 |
| 普信投资管理T. Rowe Price Investment Management, Inc. |
| 0.02% | 0.01% | #98 | $3,302.9万 | 58.1万股 | $1,546.8万 | 52.1万股 | +6.1万股+11.68% | 加仓 |
| Fiera资本Fiera Capital Corp |
| 0.11% | 0.09% | #56 | $2,937.1万 | 51.7万股 | $2,676.5万 | 90.1万股 | -38.4万股-42.61% | 减仓 |
| PanAgora资产管理PANAGORA ASSET MANAGEMENT INC |
| 0.09% | 0.07% | #58 | $2,787.8万 | 49.1万股 | $1,761.5万 | 59.3万股 | -10.2万股-17.23% | 减仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.03% | — | #91 | $2,720.4万 | 47.9万股 | $0 | 0股 | +47.9万股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #182 | $2,689.7万 | 47.3万股 | $2,545.4万 | 85.7万股 | -38.3万股-44.74% | 减仓 |
| 卢米斯塞勒斯LOOMIS SAYLES & CO L P |
| 0.03% | 0.01% | #86 | $2,675.3万 | 47.1万股 | $895.7万 | 30.1万股 | +16.9万股+56.21% | 加仓 |
| 英国法通集团Legal & General Group Plc |
| 0.01% | <0.01% | #163 | $2,672.3万 | 47.0万股 | $1,340.1万 | 45.1万股 | +1.9万股+4.29% | 加仓 |
| 康得利安资管Candriam S.C.A. |
| 0.12% | 0.09% | #52 | $2,669.0万 | 47.0万股 | $1,790.4万 | 46.9万股 | +1,709股+0.36% | 加仓 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #204 | $2,609.4万 | 45.9万股 | $1,555.9万 | 52.4万股 | -6.4万股-12.30% | 减仓 |
| 格雷厄姆资本管理Graham Capital Management, L.P. |
| 0.46% | — | #32 | $2,537.7万 | 44.7万股 | $0 | 0股 | +44.7万股 | 新买入 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #228 | $2,438.6万 | 42.9万股 | $2,669.7万 | 111.7万股 | -68.8万股-61.57% | 减仓 |
| Assenagon资产管理Assenagon Asset Management S.A. |
| 0.03% | <0.01% | #90 | $2,427.5万 | 42.7万股 | $23.6万 | 7,927股 | +41.9万股+5,290.50% | 加仓 |
| GW&K Investment Management, LLC |
| 0.18% | 0.04% | #46 | $2,296.3万 | 40.4万股 | $417.3万 | 14.0万股 | +26.4万股+187.78% | 加仓 |
| 罗素投资集团Russell Investments Group, Ltd. |
| 0.02% | 0.01% | #109 | $2,249.5万 | 39.6万股 | $696.0万 | 23.4万股 | +16.2万股+69.03% | 加仓 |
