| 富达投资FMR LLC |
| 0.03% | 0.03% | #81 | $7.05亿 | 757.2万股 | $5.07亿 | 570.9万股 | +186.3万股+32.62% | 加仓 |
| PRIMECAP管理PRIMECAP MANAGEMENT CO/CA/ |
| 0.21% | 0.27% | #31 | $3.51亿 | 377.2万股 | $3.37亿 | 379.4万股 | -2.2万股-0.57% | 减仓 |
| 道奇与考克斯DODGE & COX |
| 0.18% | 0.18% | #35 | $3.42亿 | 367.8万股 | $3.27亿 | 367.7万股 | +800股+0.02% | 加仓 |
| Flossbach von StorchFLOSSBACH VON STORCH SE |
| 0.94% | 1.53% | #12 | $2.07亿 | 222.6万股 | $3.27亿 | 368.0万股 | -145.4万股-39.51% | 减仓 |
| 普信投资管理T. Rowe Price Investment Management, Inc. |
| 0.13% | 0.36% | #39 | $1.92亿 | 206.5万股 | $5.20亿 | 585.6万股 | -379.1万股-64.73% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #166 | $1.73亿 | 185.5万股 | $1.47亿 | 165.8万股 | +19.7万股+11.87% | 加仓 |
| 淡马锡控股Temasek Holdings (Private) Ltd |
| 0.38% | 0.44% | #21 | $1.40亿 | 150.6万股 | $1.34亿 | 150.6万股 | 00.00% | 持仓不变 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| 0.06% | 0.07% | #60 | $1.23亿 | 132.0万股 | $1.48亿 | 165.2万股 | -33.2万股-20.12% | 减仓 |
| Logos Global Management LP |
| 4.07% | — | #3 | $9,444.6万 | 101.5万股 | $0 | 0股 | +101.5万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| 0.01% | 0.02% | #122 | $8,739.2万 | 93.9万股 | $1.37亿 | 154.1万股 | -60.1万股-39.04% | 减仓 |
| GSK plc |
| 13.75% | 13.2% | #1 | $8,279.8万 | 89.0万股 | $7,908.8万 | 89.0万股 | 00.00% | 持仓不变 |
| SquarepointSquarepoint Ops LLC |
| 0.08% | 0.01% | #50 | $7,623.6万 | 81.9万股 | $1,092.8万 | 12.3万股 | +69.6万股+566.38% | 加仓 |
| 第一信托顾问FIRST TRUST ADVISORS LP |
| 0.04% | 0.05% | #70 | $7,364.6万 | 79.1万股 | $7,465.8万 | 84.0万股 | -4.9万股-5.78% | 减仓 |
| Davern Capital Partners, LP |
| 11.97% | 7.44% | #2 | $7,021.1万 | 75.5万股 | $2,711.3万 | 30.5万股 | +44.9万股+147.35% | 加仓 |
| 瑞银资产管理(美洲)UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| 0.01% | 0.01% | #114 | $6,924.8万 | 74.4万股 | $6,968.1万 | 78.4万股 | -4.0万股-5.08% | 减仓 |
| MFS马萨诸塞金融服务MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
| 0.02% | 0.02% | #92 | $6,306.1万 | 67.8万股 | $5,959.5万 | 67.1万股 | +7,194股+1.07% | 加仓 |
| Long Focus 资本管理Long Focus Capital Management, LLC |
| 1.49% | 1.46% | #9 | $5,806.3万 | 62.4万股 | $5,546.1万 | 62.4万股 | 00.00% | 持仓不变 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | 0.01% | #147 | $5,710.6万 | 61.4万股 | $6,787.4万 | 76.4万股 | -15.0万股-19.64% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #143 | $5,605.4万 | 60.2万股 | $860.6万 | 9.7万股 | +50.6万股+522.13% | 加仓 |
| 百利吉福德BAILLIE GIFFORD & CO |
| 0.05% | 0.08% | #65 | $5,512.1万 | 59.2万股 | $7,844.3万 | 88.3万股 | -29.0万股-32.88% | 减仓 |
| 胜利资本管理VICTORY CAPITAL MANAGEMENT INC |
| 0.03% | 0.03% | #83 | $5,022.7万 | 54.0万股 | $4,238.9万 | 47.7万股 | +6.3万股+13.18% | 加仓 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| 0.01% | 0.01% | #120 | $5,020.9万 | 54.0万股 | $3,418.6万 | 38.5万股 | +15.5万股+40.29% | 加仓 |
| 康得利安资管Candriam S.C.A. |
| 0.21% | 0.29% | #30 | $4,625.1万 | 49.8万股 | $5,759.0万 | 60.5万股 | -10.7万股-17.75% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #168 | $4,578.9万 | 49.2万股 | $5,947.0万 | 60.3万股 | -11.1万股-18.39% | 减仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | 0.01% | #162 | $4,524.1万 | 48.6万股 | $8,026.1万 | 90.3万股 | -41.7万股-46.16% | 减仓 |
| 花旗集团CITIGROUP INC |
| 0.01% | 0.02% | #106 | $4,510.9万 | 48.5万股 | $3,645.6万 | 41.0万股 | +7.5万股+18.19% | 加仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| 0.02% | 0.01% | #90 | $4,488.9万 | 48.2万股 | $2,353.3万 | 26.5万股 | +21.8万股+82.21% | 加仓 |
| DekaBank Deutsche Girozentrale |
| 0.07% | 0.07% | #55 | $4,479.4万 | 48.1万股 | $4,205.5万 | 48.1万股 | 00.00% | 持仓不变 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| 0.06% | 0.01% | #63 | $4,473.5万 | 48.1万股 | $1,059.0万 | 11.9万股 | +36.2万股+303.48% | 加仓 |
| TANG CAPITAL MANAGEMENT LLC |
| 1.99% | 2.12% | #6 | $4,373.4万 | 47.0万股 | $4,177.4万 | 47.0万股 | 00.00% | 持仓不变 |
| Assenagon资产管理Assenagon Asset Management S.A. |
| 0.05% | — | #66 | $3,938.5万 | 42.3万股 | $0 | 0股 | +42.3万股 | 新买入 |
| LBP资产管理LBP AM SA |
| 0.36% | 0.47% | #22 | $3,615.0万 | 38.8万股 | $3,422.8万 | 38.5万股 | +3,389股+0.88% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| 0.03% | 0.02% | #84 | $3,561.2万 | 38.2万股 | $2,254.5万 | 25.4万股 | +12.8万股+50.19% | 加仓 |
| DZ 银行 AG Deutsche Zentral Genossenschafts 银行 Frankfurt am MainDZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main |
| 0.03% | 0.03% | #86 | $3,528.5万 | 37.9万股 | $3,438.2万 | 38.7万股 | -8,133股-2.10% | 减仓 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| 0.01% | 0.01% | #121 | $3,512.0万 | 37.7万股 | $3,481.3万 | 39.2万股 | -1.4万股-3.64% | 减仓 |
| SG Americas Securities, LLC |
| 0.02% | 0.03% | #100 | $3,230.1万 | 34.7万股 | $2,401.9万 | 27.0万股 | +7.7万股+28.45% | 加仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| 0.03% | — | #79 | $3,044.4万 | 32.7万股 | $0 | 0股 | +32.7万股 | 新买入 |
| 英国法通集团Legal & General Group Plc |
| 0.01% | 0.01% | #135 | $2,983.0万 | 32.0万股 | $3,104.6万 | 35.0万股 | -3.0万股-8.49% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| 0.02% | 0.01% | #93 | $2,743.2万 | 29.5万股 | $1,477.0万 | 16.6万股 | +12.9万股+77.41% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | 0.01% | #171 | $2,680.7万 | 28.8万股 | $5,691.5万 | 64.0万股 | -35.2万股-55.01% | 减仓 |
| 加拿大养老金计划投资委员会(CPPIB)CANADA PENSION PLAN INVESTMENT BOARD |
| 0.01% | 0.02% | #108 | $2,576.2万 | 27.7万股 | $2,697.6万 | 30.4万股 | -2.7万股-8.78% | 减仓 |
| Walleye交易Walleye Trading LLC |
| 0.03% | 0.04% | #82 | $2,555.1万 | 27.5万股 | $2,329.8万 | 26.2万股 | +1.2万股+4.75% | 加仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #159 | $2,524.0万 | 27.1万股 | $2,260.5万 | 25.4万股 | +1.7万股+6.65% | 加仓 |
| 哈德逊湾资本管理Hudson Bay Capital Management LP |
| 0.07% | 0.08% | #56 | $2,419.3万 | 26.0万股 | $2,444.2万 | 27.5万股 | -1.5万股-5.45% | 减仓 |
| CenterBook Partners LP |
| 1.15% | 0.82% | #11 | $2,336.3万 | 25.1万股 | $1,521.3万 | 17.1万股 | +8.0万股+46.69% | 加仓 |
| 野村资产管理国际NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
| 0.03% | 0.04% | #78 | $2,320.7万 | 24.9万股 | $2,308.5万 | 26.0万股 | -1.0万股-3.98% | 减仓 |
| SEB资产管理SEB Asset Management AB |
| 0.09% | 0.08% | #49 | $2,282.4万 | 24.5万股 | $1,780.4万 | 20.0万股 | +4.5万股+22.47% | 加仓 |
| Voloridge投资管理VOLORIDGE INVESTMENT MANAGEMENT, LLC |
| 0.1% | 0.11% | #46 | $2,265.0万 | 24.3万股 | $2,736.3万 | 30.8万股 | -6.4万股-20.93% | 减仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #165 | $1,970.4万 | 21.2万股 | $2,083.7万 | 23.4万股 | -2.3万股-9.67% | 减仓 |
| 百达资产管理Pictet Asset Management Holding SA |
| 0.02% | 0.01% | #98 | $1,751.4万 | 18.6万股 | $1,123.6万 | 13.2万股 | +5.4万股+40.98% | 加仓 |
