| Merck & Co., Inc. |
| 0.71% | — | #1 | $376.4万 | 121.4万股 | $0 | 0股 | +121.4万股 | 新买入 |
| Ikarian Capital, LLC |
| 0.02% | 0.02% | #2 | $23.2万 | 7.5万股 | $27.8万 | 7.5万股 | 00.00% | 持仓不变 |
| Rathbones集团Rathbones Group PLC |
| <0.01% | <0.01% | #10 | $14.2万 | 4.6万股 | $17.0万 | 4.6万股 | 00.00% | 持仓不变 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #15 | $11.3万 | 3.7万股 | $6.6万 | 1.8万股 | +1.9万股+105.84% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #12 | $10.5万 | 3.4万股 | $14.6万 | 3.9万股 | -5,425股-13.83% | 减仓 |
| Annis Gardner Whiting Capital Advisors, LLC |
| 0.01% | 0.02% | #3 | $9.3万 | 3.0万股 | $11.2万 | 3.0万股 | 00.00% | 持仓不变 |
| J·萨夫拉·萨拉辛控股J. Safra Sarasin Holding AG |
| <0.01% | — | #6 | $7.1万 | 2.3万股 | $0 | 0股 | +2.3万股 | 新买入 |
| RhumbLine顾问RHUMBLINE ADVISERS |
| <0.01% | <0.01% | #13 | $6.8万 | 2.2万股 | $8.1万 | 2.2万股 | +190股+0.88% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | — | #17 | $6.4万 | 2.1万股 | $0 | 0股 | +2.1万股 | 新买入 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| <0.01% | <0.01% | #8 | $5.7万 | 1.8万股 | $6.9万 | 1.8万股 | 00.00% | 持仓不变 |
| Stonepine Capital Management, LLC |
| 0.01% | 0.03% | #5 | $5.4万 | 1.8万股 | $7.3万 | 2.0万股 | -2,151股-10.91% | 减仓 |
| SmartHarvest Portfolios, LLC |
| 0.01% | 0.02% | #4 | $4.2万 | 1.3万股 | $5.1万 | 1.4万股 | -348股-2.52% | 减仓 |
| XTX资本XTX Topco Ltd |
| <0.01% | <0.01% | #11 | $4.0万 | 1.3万股 | $8.2万 | 2.2万股 | -9,154股-41.51% | 减仓 |
| WESBANCO 银行WESBANCO BANK INC |
| <0.01% | <0.01% | #7 | $3.1万 | 1.0万股 | $3.7万 | 1.0万股 | 00.00% | 持仓不变 |
| 西北互惠财富管理NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO |
| <0.01% | <0.01% | #14 | $2.5万 | 8,000股 | $3.0万 | 8,000股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | — | #19 | $1.9万 | 6,275股 | $0 | 0股 | +6,275股 | 新买入 |
| GAMMA Investing LLC |
| <0.01% | <0.01% | #9 | $1.4万 | 4,612股 | $1.9万 | 5,198股 | -586股-11.27% | 减仓 |
| Integrated Wealth ConceptsIntegrated Wealth Concepts LLC |
| <0.01% | — | #16 | $1,990 | 642股 | $0 | 0股 | +642股 | 新买入 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #18 | $192 | 62股 | $231 | 62股 | 00.00% | 持仓不变 |
