| Flagship Pioneering, LLC |
| 0.59% | 0.88% | #2 | $912.0万 | 115.6万股 | $1,025.2万 | 115.6万股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #14 | $227.1万 | 28.8万股 | $260.9万 | 29.4万股 | -6,367股-2.16% | 减仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #6 | $135.9万 | 17.2万股 | $123.8万 | 14.0万股 | +3.3万股+23.44% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #11 | $105.1万 | 13.3万股 | $201.3万 | 22.7万股 | -9.4万股-41.29% | 减仓 |
| 冯托贝尔控股Vontobel Holding Ltd. |
| <0.01% | <0.01% | #4 | $97.0万 | 12.3万股 | $122.8万 | 13.8万股 | -1.5万股-11.19% | 减仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #21 | $87.6万 | 11.1万股 | $90.5万 | 10.2万股 | +8,974股+8.80% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #16 | $63.1万 | 8.0万股 | $66.4万 | 7.5万股 | +5,139股+6.87% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #13 | $42.6万 | 5.4万股 | $52.8万 | 6.0万股 | -5,496股-9.24% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #10 | $38.4万 | 4.9万股 | $35.2万 | 4.0万股 | +9,042股+22.81% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #24 | $26.7万 | 3.4万股 | $30.1万 | 3.4万股 | 00.00% | 持仓不变 |
| Lion Point Capital, LP |
| 1.19% | 1.67% | #1 | $24.9万 | 3.2万股 | $28.0万 | 3.2万股 | 00.00% | 持仓不变 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #17 | $24.5万 | 3.1万股 | $28.1万 | 3.2万股 | -581股-1.84% | 减仓 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | <0.01% | #9 | $22.3万 | 2.8万股 | $55.3万 | 6.2万股 | -3.4万股-54.57% | 减仓 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #5 | $16.4万 | 2.1万股 | $0 | 0股 | +2.1万股 | 新买入 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | — | #22 | $12.0万 | 1.5万股 | $0 | 0股 | +1.5万股 | 新买入 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #20 | $11.6万 | 1.5万股 | $13.1万 | 1.5万股 | 00.00% | 持仓不变 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #23 | $10.2万 | 1.3万股 | $12.9万 | 1.5万股 | -1,573股-10.81% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #26 | $9.6万 | 1.2万股 | $35.3万 | 1.8万股 | -6,196股-33.80% | 减仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #19 | $3.6万 | 4,598股 | $2.7万 | 3,070股 | +1,528股+49.77% | 加仓 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #7 | $3.3万 | 4,182股 | $3.1万 | 3,482股 | +700股+20.10% | 加仓 |
| Integrated Wealth ConceptsIntegrated Wealth Concepts LLC |
| <0.01% | — | #8 | $3.2万 | 4,000股 | $0 | 0股 | +4,000股 | 新买入 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #15 | $2.9万 | 3,714股 | $7,309 | 824股 | +2,890股+350.73% | 加仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | — | #27 | $2.8万 | 3,636股 | $0 | 0股 | +3,636股 | 新买入 |
| 先锋环球顾问Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #25 | $1.6万 | 1,975股 | $1.8万 | 1,975股 | 00.00% | 持仓不变 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #30 | $1.2万 | 1,528股 | $1.6万 | 1,752股 | -224股-12.79% | 减仓 |
| Rachor Investment Advisory Services, LLC |
| 0.01% | 0.01% | #3 | $1.2万 | 1,477股 | $1.3万 | 1,477股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #31 | $3,818 | 484股 | $6.2万 | 7,030股 | -6,546股-93.12% | 减仓 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #12 | $2,493 | 316股 | $7,043 | 794股 | -478股-60.20% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #29 | $1,665 | 211股 | $1,872 | 211股 | 00.00% | 持仓不变 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #33 | $1,318 | 167股 | $5.8万 | 6,507股 | -6,340股-97.43% | 减仓 |
| Continuum Advisory, LLC |
| <0.01% | — | #18 | $371 | 47股 | $0 | 0股 | +47股 | 新买入 |
| 美世全球顾问MERCER GLOBAL ADVISORS INC /ADV |
| <0.01% | — | #32 | $292 | 37股 | $0 | 0股 | +37股 | 新买入 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #36 | $79 | 10股 | $89 | 10股 | 00.00% | 持仓不变 |
| OSAIC控股OSAIC HOLDINGS, INC. |
| <0.01% | <0.01% | #35 | $63 | 8股 | $70 | 8股 | 00.00% | 持仓不变 |
| Larson Financial 集团Larson Financial Group LLC |
| <0.01% | — | #28 | $39 | 5股 | $0 | 0股 | +5股 | 新买入 |
| 惠蒂尔信托WHITTIER TRUST CO OF NEVADA INC |
| <0.01% | — | #34 | $8 | 1股 | $0 | 0股 | +1股 | 新买入 |
