| ARCH Venture Management, LLC |
| 0.61% | — | #1 | $673.5万 | 269.4万股 | $0 | 0股 | +269.4万股 | 新买入 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #23 | $645.3万 | 258.1万股 | $296.5万 | 269.5万股 | -11.4万股-4.24% | 减仓 |
| TANG CAPITAL MANAGEMENT LLC |
| 0.29% | — | #2 | $640.0万 | 256.0万股 | $0 | 0股 | +256.0万股 | 新买入 |
| ADAR1 Capital Management, LLC |
| 0.23% | — | #3 | $492.1万 | 196.8万股 | $0 | 0股 | +196.8万股 | 新买入 |
| Cormorant Asset Management, LP |
| 0.13% | — | #5 | $250.0万 | 100.0万股 | $0 | 0股 | +100.0万股 | 新买入 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #28 | $153.7万 | 61.5万股 | $65.7万 | 59.7万股 | +1.8万股+2.97% | 加仓 |
| 惠灵顿管理集团WELLINGTON MANAGEMENT GROUP LLP |
| <0.01% | <0.01% | #24 | $139.1万 | 55.6万股 | $61.2万 | 55.6万股 | 00.00% | 持仓不变 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #21 | $119.7万 | 47.9万股 | $11.0万 | 10.0万股 | +37.9万股+379.24% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #16 | $117.9万 | 47.2万股 | $43.9万 | 39.9万股 | +7.3万股+18.19% | 加仓 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| <0.01% | <0.01% | #15 | $75.0万 | 30.0万股 | $33.0万 | 30.0万股 | 00.00% | 持仓不变 |
| Affinity Asset Advisors, LLC |
| 0.03% | — | #8 | $62.5万 | 25.0万股 | $0 | 0股 | +25.0万股 | 新买入 |
| RBF Capital, LLC |
| 0.02% | 0.01% | #9 | $50.0万 | 20.0万股 | $22.0万 | 20.0万股 | 00.00% | 持仓不变 |
| Ensign Peak顾问Ensign Peak Advisors, Inc |
| <0.01% | <0.01% | #18 | $40.0万 | 16.0万股 | $20.6万 | 18.8万股 | -2.8万股-14.75% | 减仓 |
| Stonepine Capital Management, LLC |
| 0.06% | 0.26% | #7 | $38.6万 | 15.5万股 | $65.7万 | 59.8万股 | -44.3万股-74.13% | 减仓 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #20 | $36.7万 | 14.7万股 | $1.2万 | 1.3万股 | +13.4万股+1,063.81% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #26 | $36.3万 | 14.5万股 | $147.6万 | 134.2万股 | -119.7万股-89.19% | 减仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| 0.01% | <0.01% | #12 | $32.0万 | 12.8万股 | $5.6万 | 5.1万股 | +7.8万股+153.47% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #30 | $29.2万 | 11.7万股 | $14.0万 | 12.8万股 | -1.1万股-8.50% | 减仓 |
| HRT金融HRT FINANCIAL LP |
| <0.01% | — | #19 | $29.1万 | 11.6万股 | $0 | 0股 | +11.6万股 | 新买入 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #33 | $22.1万 | 8.8万股 | $7.8万 | 7.1万股 | +1.8万股+25.21% | 加仓 |
| PRELUDE CAPITAL MANAGEMENT, LLC |
| 0.01% | — | #10 | $21.0万 | 8.4万股 | $0 | 0股 | +8.4万股 | 新买入 |
| Rangeley Capital, LLC |
| 0.18% | — | #4 | $18.5万 | 7.4万股 | $0 | 0股 | +7.4万股 | 新买入 |
| GSA CAPITAL PARTNERS LLP |
| 0.01% | 0.01% | #11 | $18.1万 | 7.2万股 | $10.7万 | 9.7万股 | -2.4万股-25.27% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #27 | $16.3万 | 6.5万股 | $7.2万 | 6.5万股 | 00.00% | 持仓不变 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | — | #31 | $16.1万 | 6.4万股 | $0 | 0股 | +6.4万股 | 新买入 |
| SUPERSTRING CAPITAL MANAGEMENT LP |
| 0.09% | — | #6 | $13.8万 | 5.5万股 | $0 | 0股 | +5.5万股 | 新买入 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | — | #32 | $8.7万 | 3.5万股 | $0 | 0股 | +3.5万股 | 新买入 |
| XTX资本XTX Topco Ltd |
| <0.01% | <0.01% | #17 | $8.3万 | 3.3万股 | $3.8万 | 3.5万股 | -1,310股-3.78% | 减仓 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #25 | $5.1万 | 2.0万股 | $1.9万 | 1.7万股 | +2,715股+15.52% | 加仓 |
| China Universal Asset Management Co., Ltd. |
| <0.01% | — | #14 | $4.2万 | 1.7万股 | $0 | 0股 | +1.7万股 | 新买入 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #35 | $4.0万 | 1.6万股 | $1.8万 | 1.6万股 | 00.00% | 持仓不变 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #34 | $3.3万 | 1.3万股 | $1.9万 | 1.6万股 | -2,501股-16.13% | 减仓 |
| Caitong International Asset Management Co., Ltd |
| <0.01% | <0.01% | #13 | $2.6万 | 1.0万股 | $3 | 3股 | +1.0万股+348,000.00% | 加仓 |
| 纯粹金融顾问Pure Financial Advisors, LLC |
| <0.01% | <0.01% | #22 | $2.5万 | 1.0万股 | $1.1万 | 1.0万股 | 00.00% | 持仓不变 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #29 | $870 | 348股 | $2,608 | 2,371股 | -2,023股-85.32% | 减仓 |
| 法国巴黎银行金融市场BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #37 | $440 | 176股 | $196 | 178股 | -2股-1.12% | 减仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #40 | $439 | 179股 | $183 | 169股 | +10股+5.92% | 加仓 |
| 美世全球顾问MERCER GLOBAL ADVISORS INC /ADV |
| <0.01% | — | #38 | $125 | 50股 | $0 | 0股 | +50股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #41 | $5 | 2股 | $2 | 2股 | 00.00% | 持仓不变 |
| Financial Management Professionals, Inc. |
| <0.01% | — | #36 | $5 | 2股 | $0 | 0股 | +2股 | 新买入 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #39 | $5 | 2股 | $1 | 1股 | +1股+100.00% | 加仓 |
