| Opaleye Management Inc. |
| 1.89% | 1.85% | #3 | $2,090.5万 | 289.5万股 | $1,406.5万 | 256.2万股 | +33.4万股+13.02% | 加仓 |
| Solas Capital Management, LLC |
| 7.45% | 6.08% | #1 | $1,389.6万 | 192.5万股 | $1,056.6万 | 192.5万股 | 00.00% | 持仓不变 |
| AWM Investment Company, Inc. |
| 1.05% | 1.02% | #4 | $1,207.3万 | 167.2万股 | $918.0万 | 167.2万股 | 00.00% | 持仓不变 |
| Cable Car 资本Cable Car Capital, LP |
| 2.47% | 2.52% | #2 | $758.9万 | 138.2万股 | $758.9万 | 138.2万股 | 00.00% | 持仓不变 |
| Ikarian Capital, LLC |
| 0.64% | 0.47% | #5 | $603.8万 | 83.6万股 | $579.9万 | 105.6万股 | -22.0万股-20.83% | 减仓 |
| SPHERA FUNDS MANAGEMENT LTD. |
| 0.51% | 0.49% | #6 | $394.1万 | 54.6万股 | $311.6万 | 56.8万股 | -2.2万股-3.84% | 减仓 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| 0.01% | 0.01% | #12 | $263.5万 | 36.5万股 | $200.4万 | 36.5万股 | 00.00% | 持仓不变 |
| Aristides Capital LLC |
| 0.31% | 0.26% | #7 | $157.8万 | 21.9万股 | $120.0万 | 21.9万股 | 00.00% | 持仓不变 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| 0.02% | 0.02% | #10 | $136.6万 | 18.9万股 | $140.8万 | 25.6万股 | -6.7万股-26.23% | 减仓 |
| 康托·菲茨杰拉德CANTOR FITZGERALD, L. P. |
| 0.01% | 0.02% | #11 | $78.6万 | 10.9万股 | $103.6万 | 18.9万股 | -8.0万股-42.26% | 减仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #16 | $70.4万 | 9.8万股 | $49.2万 | 9.0万股 | +7,957股+8.88% | 加仓 |
| VILLERE ST DENIS J & CO LLC |
| 0.06% | 0.04% | #9 | $51.4万 | 7.1万股 | $39.1万 | 7.1万股 | 00.00% | 持仓不变 |
| 都铎投资TUDOR INVESTMENT CORP ET AL |
| <0.01% | <0.01% | #14 | $44.5万 | 6.2万股 | $33.8万 | 6.2万股 | 00.00% | 持仓不变 |
| ACT CAPITAL MANAGEMENT, LLC |
| 0.24% | 0.22% | #8 | $37.2万 | 5.2万股 | $28.3万 | 5.2万股 | 00.00% | 持仓不变 |
| BERKSHIRE ASSET MANAGEMENT LLC/PA |
| 0.01% | — | #13 | $14.3万 | 2.0万股 | $0 | 0股 | +2.0万股 | 新买入 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #15 | $13.6万 | 1.9万股 | $8.7万 | 1.6万股 | +2,946股+18.54% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #21 | $8.7万 | 1.2万股 | $6.6万 | 1.2万股 | 00.00% | 持仓不变 |
| 雷蒙德詹姆斯金融RAYMOND JAMES FINANCIAL INC |
| <0.01% | <0.01% | #19 | $7.2万 | 1.0万股 | $5.5万 | 1.0万股 | 00.00% | 持仓不变 |
| 加拿大国家银行NATIONAL BANK OF CANADA /FI/ |
| <0.01% | <0.01% | #17 | $3.8万 | 5,292股 | $2.8万 | 5,292股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #23 | $1.1万 | 1,456股 | $2,405 | 438股 | +1,018股+232.42% | 加仓 |
| Allworth金融Allworth Financial LP |
| <0.01% | <0.01% | #18 | $5,415 | 750股 | $4,118 | 750股 | 00.00% | 持仓不变 |
| 琼斯金融JONES FINANCIAL COMPANIES LLLP |
| <0.01% | <0.01% | #24 | $1,625 | 250股 | $508 | 100股 | +150股+150.00% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #26 | $1,444 | 200股 | $5,468 | 840股 | -640股-76.19% | 减仓 |
| Steward合伙人投资顾问Steward Partners Investment Advisory, LLC |
| <0.01% | <0.01% | #20 | $1,444 | 200股 | $1,098 | 200股 | 00.00% | 持仓不变 |
| 加拿大皇家银行ROYAL BANK OF CANADA |
| <0.01% | <0.01% | #25 | $1,000 | 122股 | $4,000 | 679股 | -557股-82.03% | 减仓 |
| 港湾投资HARBOUR INVESTMENTS, INC. |
| <0.01% | <0.01% | #22 | $336 | 47股 | $25 | 4股 | +43股+1,075.00% | 加仓 |
