| FMR LLC |
| 0.2% | 0.25% | #85 | $4.52B | 15.0M | $4.82B | 14.6M | +444,796+3.05% | Add |
| Capital World Investors |
| 0.4% | 0.49% | #43 | $3.35B | 11.1M | $3.57B | 10.8M | +342,498+3.17% | Add |
| BlackRock, Inc. |
| 0.05% | 0.06% | #243 | $3.28B | 10.9M | $3.46B | 10.4M | +462,767+4.43% | Add |
| Capital Research Global Investors |
| 0.41% | 0.49% | #41 | $2.94B | 9.8M | $3.13B | 9.5M | +279,518+2.95% | Add |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| 0.09% | 0.11% | #146 | $1.97B | 6.5M | $2.15B | 6.5M | +47,110+0.73% | Add |
| VANGUARD CAPITAL MANAGEMENT LLC |
| 0.04% | 0.05% | #285 | $1.82B | 6.0M | $1.97B | 5.9M | +82,772+1.39% | Add |
| T. Rowe Price Investment Management, Inc. |
| 1.11% | 1.18% | #14 | $1.70B | 5.6M | $1.72B | 5.2M | +448,849+8.64% | Add |
| Invesco Ltd. |
| 0.09% | 0.06% | #145 | $1.13B | 3.8M | $427.4M | 1.3M | +2.5M+190.64% | Add |
| STATE STREET CORP |
| 0.03% | 0.04% | #320 | $1.07B | 3.6M | $1.10B | 3.3M | +232,991+7.01% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| 0.04% | 0.06% | #274 | $791.3M | 2.6M | $884.6M | 2.7M | -24,545-0.92% | Reduce |
| JPMORGAN CHASE & CO |
| 0.04% | 0.13% | #267 | $785.3M | 2.7M | $2.00B | 6.3M | -3.6M-57.69% | Reduce |
| BAILLIE GIFFORD & CO |
| 0.67% | 0.8% | #25 | $734.5M | 2.4M | $825.1M | 2.5M | -53,977-2.16% | Reduce |
| NORGES BANK |
| 0.07% | 0.08% | #174 | $683.9M | 2.3M | $576.8M | 2.1M | +135,789+6.36% | Add |
| WELLINGTON MANAGEMENT GROUP LLP |
| 0.11% | 0.12% | #128 | $635.3M | 2.1M | $640.5M | 1.9M | +174,482+9.01% | Add |
| Orbis Allan Gray Ltd |
| 2.06% | 1.86% | #8 | $598.3M | 2.0M | $441.7M | 1.3M | +652,582+48.89% | Add |
| DODGE & COX |
| 0.31% | 0.35% | #57 | $588.6M | 2.0M | $638.3M | 1.9M | +26,140+1.35% | Add |
| TWO SIGMA INVESTMENTS, LP |
| 0.41% | 0.53% | #42 | $564.7M | 1.9M | $659.3M | 2.0M | -116,640-5.85% | Reduce |
| AMERICAN CENTURY COMPANIES INC |
| 0.25% | 0.31% | #68 | $558.1M | 1.9M | $596.3M | 1.8M | +51,593+2.86% | Add |
| D. E. Shaw & Co., Inc. |
| 0.22% | 0.29% | #76 | $461.9M | 1.5M | $487.8M | 1.5M | +60,047+4.07% | Add |
| Clearbridge Investments, LLC |
| 0.31% | 0.39% | #55 | $379.1M | 1.3M | $448.7M | 1.4M | -96,553-7.12% | Reduce |
| PRICE T ROWE ASSOCIATES INC /MD/ |
| 0.03% | 0.05% | #309 | $345.9M | 1.1M | $474.1M | 1.4M | -283,547-19.79% | Reduce |
| MORGAN STANLEY |
| 0.02% | 0.02% | #419 | $310.7M | 1.0M | $331.1M | 726,061 | +306,089+42.16% | Add |
| BANK OF AMERICA CORP /DE/ |
| 0.02% | 0.02% | #398 | $299.4M | 994,476 | $319.9M | 966,912 | +27,564+2.85% | Add |
| Legal & General Group Plc |
| 0.06% | 0.07% | #201 | $278.3M | 924,561 | $309.3M | 934,881 | -10,320-1.10% | Reduce |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
| 0.21% | 0.19% | #80 | $269.1M | 893,795 | $219.2M | 662,365 | +231,430+34.94% | Add |
| ROYAL BANK OF CANADA |
| 0.04% | 0.05% | #278 | $268.2M | 890,859 | $261.9M | 791,515 | +99,344+12.55% | Add |
| NORTHERN TRUST CORP |
| 0.03% | 0.04% | #323 | $267.0M | 886,900 | $283.9M | 858,120 | +28,780+3.35% | Add |
| VANGUARD FIDUCIARY TRUST CO |
| 0.06% | 0.07% | #206 | $259.7M | 862,782 | $278.2M | 840,888 | +21,894+2.60% | Add |
| DEUTSCHE BANK AG\ |
| 0.07% | 0.08% | #169 | $248.6M | 825,800 | $255.4M | 771,864 | +53,936+6.99% | Add |
| Deep Track Capital, LP |
| 3.61% | — | #3 | $248.3M | 825,000 | $0 | 0 | +825,000 | New Buy |
| Qube Research & Technologies Ltd |
| 0.22% | 0.31% | #74 | $240.4M | 798,715 | $277.3M | 838,187 | -39,472-4.71% | Reduce |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| 0.02% | 0.02% | #403 | $240.3M | 798,160 | $197.5M | 596,768 | +201,392+33.75% | Add |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| 0.03% | 0.03% | #327 | $227.4M | 755,377 | $222.8M | 673,356 | +82,021+12.18% | Add |
| LOS ANGELES CAPITAL MANAGEMENT LLC |
| 0.81% | 0.12% | #20 | $219.6M | 729,635 | $29.2M | 88,278 | +641,357+726.52% | Add |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
| 0.04% | 0.05% | #280 | $219.1M | 727,848 | $224.2M | 677,519 | +50,329+7.43% | Add |
| AQR CAPITAL MANAGEMENT LLC |
| 0.08% | 0.14% | #161 | $219.0M | 728,039 | $297.9M | 913,104 | -185,065-20.27% | Reduce |
| FEDERATED HERMES, INC. |
| 0.31% | 0.37% | #56 | $216.7M | 719,905 | $227.6M | 687,816 | +32,089+4.67% | Add |
| WELLS FARGO & COMPANY/MN |
| 0.03% | 0.04% | #313 | $204.7M | 680,047 | $235.8M | 712,763 | -32,716-4.59% | Reduce |
| UBS Group AG |
| 0.02% | 0.02% | #368 | $188.7M | 627,004 | $152.8M | 461,858 | +165,146+35.76% | Add |
| Amundi |
| 0.05% | 0.07% | #257 | $185.9M | 617,471 | $247.3M | 747,544 | -130,073-17.40% | Reduce |
| LOOMIS SAYLES & CO L P |
| 0.22% | 0.23% | #75 | $174.7M | 580,187 | $169.4M | 512,097 | +68,090+13.30% | Add |
| GOLDMAN SACHS GROUP INC |
| 0.02% | 0.02% | #434 | $173.0M | 574,757 | $155.3M | 469,388 | +105,369+22.45% | Add |
| Bank of New York Mellon Corp |
| 0.02% | 0.03% | #366 | $148.1M | 492,071 | $162.5M | 491,200 | +871+0.18% | Add |
| Polar Capital Holdings Plc |
| 0.34% | 0.3% | #47 | $145.3M | 482,751 | $85.3M | 257,674 | +225,077+87.35% | Add |
| Paradigm Biocapital Advisors LP |
| 2.71% | — | #4 | $144.5M | 480,000 | $0 | 0 | +480,000 | New Buy |
| FRANKLIN RESOURCES INC |
| 0.03% | 0.03% | #343 | $134.8M | 447,699 | $155.6M | 470,390 | -22,691-4.82% | Reduce |
| FIRST TRUST ADVISORS LP |
| 0.07% | 0.09% | #164 | $126.9M | 421,534 | $126.6M | 382,701 | +38,833+10.15% | Add |
| RAYMOND JAMES FINANCIAL INC |
| 0.03% | 0.04% | #318 | $118.2M | 392,799 | $130.0M | 406,956 | -14,157-3.48% | Reduce |
| DIMENSIONAL FUND ADVISORS LP |
| 0.02% | 0.03% | #381 | $118.0M | 392,022 | $127.1M | 384,205 | +7,817+2.03% | Add |
| MILLENNIUM MANAGEMENT LLC |
| 0.04% | 0.07% | #287 | $114.2M | 379,201 | $163.1M | 493,087 | -113,886-23.10% | Reduce |