 GUARDANT HEALTH INCGH |
| 7.41% | 5.04% | $509.1M | 3.4M | $308.4M | 3.3M | +55,071+1.65% | Add |
| IIMMUNOVANT INCIMVT |
| 5.24% | 4.68% | $359.9M | 9.3M | $286.3M | 11.5M | -2.2M-18.96% | Reduce |
 STRUCTURE THERAPEUTICS INCGPCR |
| 3.7% | 3.37% | $254.4M | 4.7M | $206.3M | 4.3M | +460,224+10.75% | Add |
 VAXCYTE INCPCVX |
| 3.64% | 4.08% | $250.0M | 4.3M | $249.9M | 4.3M | 00.00% | Unchanged |
 ALNYLAM PHARMACEUTICALS INCALNY |
| 3.61% | — | $248.3M | 825,000 | $0 | 0 | +825,000 | New Buy |
| VVERADERMICS INCMANE |
| 3.58% | 0.52% | $245.9M | 2.0M | $31.6M | 500,000 | +1.5M+300.00% | Add |
| GGENMAB A/S SPONSORED ADSGMAB |
| 3.46% | 1.61% | $237.6M | 8.7M | $98.3M | 3.7M | +5.0M+136.13% | Add |
| TTARSUS PHARMACEUTICALS INCTARS |
| 3.36% | 4.12% | $230.8M | 3.7M | $252.5M | 3.6M | +66,768+1.85% | Add |
| NNUVALENT INCNUVL |
| 3.21% | 2.3% | $220.2M | 1.8M | $141.0M | 1.4M | +406,998+29.57% | Add |
 ALKERMES PLCALKS |
| 3.05% | 2.07% | $209.6M | 4.0M | $127.0M | 3.6M | +409,677+11.41% | Add |
| OOCULAR THERAPEUTIX INCOCUL |
| 2.81% | 2.72% | $193.3M | 19.7M | $166.7M | 19.7M | 00.00% | Unchanged |
 BIOMARIN PHARMACEUTICAL INCBMRN |
| 2.75% | 1.06% | $189.3M | 3.3M | $65.0M | 1.2M | +2.2M+187.61% | Add |
 NURIX THERAPEUTICS INCNRIX |
| 2.73% | 1.61% | $187.7M | 7.7M | $98.4M | 6.3M | +1.4M+21.93% | Add |
| OORUKA THERAPEUTICS INC COMORKA |
| 2.67% | 1.63% | $183.3M | 1.9M | $99.8M | 2.0M | -108,203-5.32% | Reduce |
 ALUMIS INCALMS |
| 2.6% | 2.44% | $178.6M | 6.3M | $149.2M | 6.8M | -424,037-6.26% | Reduce |
 IONIS PHARMACEUTICALS INCIONS |
| 2.54% | 2.39% | $174.4M | 2.2M | $146.4M | 2.0M | +250,000+12.82% | Add |
 COMPASS PATHWAYS ADR A FUNSPONSORED ADR 1 ADR REPS 1 ORD SHSCMPS |
| 2.5% | 1.1% | $172.1M | 12.2M | $67.3M | 12.2M | 00.00% | Unchanged |
| VVERA THERAPEUTICS INCVERA |
| 2.5% | 2.7% | $171.6M | 4.0M | $165.2M | 4.1M | -106,067-2.58% | Reduce |
 AXSOME THERAPEUTICS INC.AXSM |
| 2.49% | 3.04% | $171.3M | 700,000 | $185.9M | 1.1M | -400,000-36.36% | Reduce |
| MMOONLAKE IMMUNOTHERAPEUTICSMLTX |
| 1.98% | 1.95% | $136.3M | 7.0M | $119.5M | 6.4M | +590,162+9.21% | Add |
| HHEMAB THERAPEUTICS HLDGS INCCOAG |
| 1.93% | — | $132.3M | 3.6M | $0 | 0 | +3.6M | New Buy |
| TTANGO THERAPEUTICS INCTNGX |
| 1.91% | 0.94% | $131.3M | 4.2M | $57.5M | 2.8M | +1.5M+52.73% | Add |
| DDEFINIUM THERAPEUTICS INCDFTX |
| 1.88% | 0.93% | $129.4M | 2.8M | $56.7M | 3.0M | -250,000-8.33% | Reduce |
 GRAIL INCGRAL |
| 1.82% | 1.45% | $125.3M | 1.8M | $89.0M | 1.7M | +112,147+6.51% | Add |
| BBICARA THERAPEUTICS INCBCAX |
| 1.77% | 1.32% | $121.7M | 4.1M | $80.8M | 4.1M | +37,500+0.92% | Add |
| MMAZE THERAPEUTICS INCMAZE |
| 1.62% | 1.7% | $111.4M | 3.7M | $103.8M | 3.5M | +255,007+7.33% | Add |
| CCELLDEX THERAPEUTICS INC NEWCLDX |
| 1.59% | 0.67% | $109.4M | 2.9M | $40.7M | 1.3M | +1.7M+128.91% | Add |
| LLB PHARMACEUTICALS INCLBRX |
| 1.58% | 1.35% | $108.8M | 3.4M | $82.7M | 3.4M | 00.00% | Unchanged |
| MMBX BIOSCIENCES INCMBX |
| 1.39% | 1.34% | $95.6M | 1.7M | $82.3M | 2.8M | -1.0M-37.17% | Reduce |
 GH RESEARCH PLC ORDINARY SHARESGHRS |
| 1.3% | — | $89.6M | 3.3M | $0 | 0 | +3.3M | New Buy |
 COGENT BIOSCIENCES INCCOGT |
| 1.13% | 0.63% | $77.4M | 2.0M | $38.5M | 1.0M | +1.0M+100.00% | Add |
| AATAIBECKLEY INCATAI |
| 1.11% | 0.69% | $76.0M | 14.4M | $42.5M | 12.0M | +2.4M+20.15% | Add |
 UNITED THERAPEUTICS CORP DELUTHR |
| 0.97% | — | $67.0M | 123,616 | $0 | 0 | +123,616 | New Buy |
 AVALO THERAPEUTICSAVTX |
| 0.97% | — | $66.7M | 3.6M | $0 | 0 | +3.6M | New Buy |
| VVIRIDIAN THERAPEUTICS INCVRDN |
| 0.96% | 0.45% | $66.0M | 3.6M | $27.3M | 1.4M | +2.2M+157.74% | Add |
 CYTOKINETICS INCCYTK |
| 0.87% | 1.48% | $59.6M | 700,000 | $90.6M | 1.4M | -674,320-49.07% | Reduce |
 ALTIMMUNE INCALT |
| 0.85% | — | $58.5M | 19.3M | $0 | 0 | +19.3M | New Buy |
 PERSONALIS INCPSNL |
| 0.78% | 0.31% | $53.6M | 4.0M | $19.1M | 3.0M | +1.0M+33.33% | Add |
| AACLARIS THERAPEUTICS INC COMACRS |
| 0.72% | 0.57% | $49.4M | 9.3M | $35.0M | 9.3M | 00.00% | Unchanged |
 CORMEDIX INCCRMD |
| 0.72% | 0.7% | $49.3M | 6.3M | $42.6M | 6.3M | 00.00% | Unchanged |
 GENEDX HOLDINGS CORPWGS |
| 0.7% | — | $48.1M | 700,000 | $0 | 0 | +700,000 | New Buy |
 HARROW INCHROW |
| 0.6% | — | $41.2M | 969,000 | $0 | 0 | +969,000 | New Buy |
 CORVUS PHARMACEUTICALS ICRVS |
| 0.54% | 0.6% | $37.2M | 2.5M | $36.5M | 2.5M | +400+0.02% | Add |
 SOLID BIOSCIENCES INCSLDB |
| 0.52% | 0.42% | $35.6M | 3.6M | $25.7M | 3.6M | 00.00% | Unchanged |
| BBEAM THERAPEUTICS INCBEAM |
| 0.5% | 0.32% | $34.3M | 1.0M | $19.6M | 820,765 | +179,235+21.84% | Add |
| DDYNE THERAPEUTICS INCDYN |
| 0.48% | 0.59% | $33.3M | 1.5M | $36.3M | 2.0M | -500,000-25.00% | Reduce |
| IIMMIX BIOPHARMA INC COMIMMX |
| 0.42% | — | $28.6M | 2.8M | $0 | 0 | +2.8M | New Buy |
| XX4 Pharmaceuticals IncXFOR |
| 0.4% | 0.43% | $27.5M | 5.9M | $26.2M | 6.3M | -460,778-7.27% | Reduce |
| SSHATTUCK LABS INCSTTK |
| 0.37% | — | $25.7M | 3.7M | $0 | 0 | +3.7M | New Buy |
 MANNKIND CORPMNKD |
| 0.37% | — | $25.6M | 6.0M | $0 | 0 | +6.0M | New Buy |
