| AASCENDIS PHARMA A/S SPONSORED ADRASND |
| 5.72% | 2.91% | $55.0M | 206,234 | $28.5M | 124,658 | +81,576+65.44% | Add |
 CELCUITY INCCELC |
| 5.45% | 4.17% | $52.4M | 500,996 | $40.9M | 357,903 | +143,093+39.98% | Add |
 COGENT BIOSCIENCES INCCOGT |
| 5.15% | 5.16% | $49.6M | 1.3M | $50.6M | 1.3M | -33,482-2.55% | Reduce |
| UUROGEN PHARMA LTDURGN |
| 4.98% | 2.76% | $47.9M | 1.3M | $27.0M | 1.5M | -201,066-13.38% | Reduce |
| IIMMUNOME INCIMNM |
| 4.44% | 4.13% | $42.7M | 2.0M | $40.5M | 1.9M | +166,731+9.01% | Add |
| DDIANTHUS THERAPEUTICS INCDNTH |
| 3.95% | 5.61% | $38.0M | 390,000 | $54.9M | 654,746 | -264,746-40.43% | Reduce |
 RHYTHM PHARMACEUTICALS INCRYTM |
| 3.59% | 2.72% | $34.6M | 311,461 | $26.6M | 306,000 | +5,461+1.78% | Add |
| OORUKA THERAPEUTICS INC COMORKA |
| 3.49% | 0.76% | $33.6M | 352,802 | $7.4M | 150,908 | +201,894+133.79% | Add |
| MMONTE ROSA THERAPEUTICS INCGLUE |
| 2.79% | 3.36% | $26.8M | 1.1M | $32.9M | 2.0M | -893,745-44.64% | Reduce |
 SYNDAX PHARMACEUTICALS INCSNDX |
| 2.76% | 2.12% | $26.5M | 1.2M | $20.8M | 888,987 | +325,403+36.60% | Add |
| EENLIVEN THERAPEUTICS INCELVN |
| 2.58% | — | $24.8M | 489,382 | $0 | 0 | +489,382 | New Buy |
| IIMMUNOVANT INCIMVT |
| 2.48% | 1.05% | $23.9M | 619,096 | $10.3M | 414,236 | +204,860+49.45% | Add |
| EERASCA INCERAS |
| 2.4% | 3.06% | $23.1M | 1.3M | $30.0M | 1.9M | -588,786-31.80% | Reduce |
| SSAGIMET BIOSCIENCES INCSGMT |
| 2.35% | — | $22.6M | 2.9M | $0 | 0 | +2.9M | New Buy |
 ABIVAX SAABVX |
| 2.35% | 3.44% | $22.6M | 169,593 | $33.7M | 302,530 | -132,937-43.94% | Reduce |
 PRAXIS PRECISION MEDICINES IPRAX |
| 2.29% | 2.35% | $22.0M | 65,679 | $23.1M | 71,552 | -5,873-8.21% | Reduce |
| KKODIAK SCIENCES INCKOD |
| 2.21% | 3.86% | $21.3M | 546,256 | $37.8M | 991,930 | -445,674-44.93% | Reduce |
| AARK ETF TR |
| 2.19% | — | $21.0M | 500,000 | $0 | 0 | +500,000 | New Buy |
| DDEFINIUM THERAPEUTICS INCDFTX |
| 1.96% | — | $18.8M | 400,000 | $0 | 0 | +400,000 | New Buy |
| VVERACYTE INCVCYT |
| 1.94% | 0.59% | $18.7M | 318,001 | $5.8M | 179,700 | +138,301+76.96% | Add |
| SSYNDAX PHARMACEUTICALS INCSNDX |
| 1.58% | 0.76% | $15.2M | 693,600 | $7.5M | 320,000 | +373,600+116.75% | Add |
 GUARDANT HEALTH INCGH |
| 1.56% | 0.93% | $15.0M | 99,826 | $9.1M | 98,514 | +1,312+1.33% | Add |
| CC4 THERAPEUTICS INC COM STKCCCC |
| 1.47% | 0.51% | $14.2M | 3.0M | $5.0M | 1.9M | +1.1M+58.60% | Add |
| ZZENAS BIOPHARMA INCZBIO |
| 1.34% | 2.27% | $12.9M | 509,789 | $22.2M | 1.1M | -626,146-55.12% | Reduce |
 TREVI THERAPEUTICS INCTRVI |
| 1.31% | 0.62% | $12.6M | 678,095 | $6.1M | 511,127 | +166,968+32.67% | Add |
| HHELIX ACQUISITION CORP IIIHLXC |
| 1.3% | 1.25% | $12.5M | 1.2M | $12.3M | 1.2M | -31,165-2.58% | Reduce |
| AALX ONCOLOGY HLDGS INCALXO |
| 1.24% | — | $11.9M | 5.7M | $0 | 0 | +5.7M | New Buy |
| VVERADERMICS INCMANE |
| 1.21% | — | $11.7M | 95,000 | $0 | 0 | +95,000 | New Buy |
 XENON PHARMACEUTICALS INCXENE |
| 1.17% | 1.17% | $11.3M | 186,821 | $11.5M | 197,759 | -10,938-5.53% | Reduce |
| AAVALYN PHARMACEUTICALS INCAVLN |
| 1.13% | — | $10.9M | 330,487 | $0 | 0 | +330,487 | New Buy |
 BIOGEN INCBIIB |
| 1.08% | 0.95% | $10.4M | 48,101 | $9.3M | 50,967 | -2,866-5.62% | Reduce |
| AACLARIS THERAPEUTICS INC COMACRS |
| 1.07% | — | $10.3M | 1.9M | $0 | 0 | +1.9M | New Buy |
| CCERUS CORPCERS |
| 1.05% | 0.59% | $10.1M | 3.5M | $5.8M | 3.2M | +296,190+9.32% | Add |
 AVALO THERAPEUTICSAVTX |
| 0.96% | — | $9.2M | 500,402 | $0 | 0 | +500,402 | New Buy |
 BENITEC BIOPHARMA INCBNTC |
| 0.95% | 0.78% | $9.1M | 679,826 | $7.6M | 717,725 | -37,899-5.28% | Reduce |
 VAXCYTE INCPCVX |
| 0.88% | 0.86% | $8.4M | 145,000 | $8.4M | 144,981 | +19+0.01% | Add |
 GENEDX HOLDINGS CORPWGS |
| 0.87% | — | $8.4M | 122,269 | $0 | 0 | +122,269 | New Buy |
| SSAVARA INCSVRA |
| 0.87% | 0.8% | $8.3M | 1.4M | $7.8M | 1.4M | -75,523-5.28% | Reduce |
| OOVID THERAPEUTICS INCOVID |
| 0.87% | 0.23% | $8.3M | 3.1M | $2.2M | 1.0M | +2.1M+210.11% | Add |
| OORIC PHARMACEUTICALS INCORIC |
| 0.83% | 1.42% | $8.0M | 738,873 | $13.9M | 1.1M | -361,137-32.83% | Reduce |
| OORIC PHARMACEUTICALS INCORIC |
| 0.77% | — | $7.4M | 682,600 | $0 | 0 | +682,600 | New Buy |
| MMONTE ROSA THERAPEUTICS INCGLUE |
| 0.75% | — | $7.3M | 300,000 | $0 | 0 | +300,000 | New Buy |
 COMPASS PATHWAYS ADR A FUNSPONSORED ADR 1 ADR REPS 1 ORD SHSCMPS |
| 0.74% | 0.17% | $7.1M | 503,382 | $1.7M | 300,000 | +203,382+67.79% | Add |
| CCOMPUGEN LTD ORDCGEN |
| 0.71% | 0.72% | $6.8M | 3.2M | $7.1M | 3.3M | -131,588-3.97% | Reduce |
 SOLID BIOSCIENCES INCSLDB |
| 0.69% | — | $6.7M | 668,450 | $0 | 0 | +668,450 | New Buy |
| AABIVAX SA SPONSORED ADS |
| 0.69% | — | $6.7M | 50,000 | $0 | 0 | +50,000 | New Buy |
| IIBIO INC CON NEWIBIO |
| 0.64% | 0.04% | $6.2M | 3.5M | $429,400 | 226,000 | +3.3M+1,457.74% | Add |
 DISC MEDICINE INCIRON |
| 0.63% | 1.28% | $6.1M | 82,800 | $12.5M | 196,028 | -113,228-57.76% | Reduce |
 ALKERMES PLCALKS |
| 0.62% | 1.66% | $5.9M | 113,494 | $16.3M | 460,314 | -346,820-75.34% | Reduce |
| SSPYRE THERAPEUTICS INCSYRE |
| 0.55% | 0.96% | $5.3M | 59,959 | $9.4M | 186,618 | -126,659-67.87% | Reduce |
