KRYSTAL BIOTECH INC KRYS
12.03% 12.06% $349.1M 939,254 $297.9M 1.2M -213,833 -18.54% Reduce CELCUITY INC CELC
6.14% 5.94% $178.3M 1.7M $146.6M 1.3M +419,940 +32.70% Add TG THERAPEUTICS INC TGTX
5.54% 5.42% $160.9M 2.9M $133.9M 4.0M -1.1M -27.34% Reduce INSULET CORP PODD
5.5% 4.78% $159.7M 1.0M $118.0M 562,500 +486,500 +86.49% Add N NOVOCURE LTD NVCR
5.18% 4.63% $150.2M 9.9M $114.4M 10.5M -578,990 -5.52% Reduce UNITED THERAPEUTICS CORP DEL UTHR
4.21% 4.5% $122.2M 225,587 $111.0M 187,187 +38,400 +20.51% Add I INSPIRE MED SYS INC INSP
2.97% 1.2% $86.2M 1.9M $29.7M 576,299 +1.4M +235.14% Add RIGEL PHARMACEUTICALS INC RIGL
2.49% 0.01% $72.1M 1.8M $270,400 10,000 +1.8M +18,335.04% Add ANI PHARMACEUTICALS INC ANIP
2.48% 2.55% $71.8M 867,760 $63.1M 820,243 +47,517 +5.79% Add B BETA BIONICS INC BBNX
2.37% 1.77% $68.8M 4.4M $43.6M 4.4M +39,213 +0.90% Add VERICEL CORP VCEL
2.24% 3.32% $64.9M 1.5M $82.0M 2.5M -1.1M -42.76% Reduce PRAXIS PRECISION MEDICINES I PRAX
2.05% 4.31% $59.4M 177,517 $106.5M 330,517 -153,000 -46.29% Reduce G GERON CORP GERN
1.89% 2.5% $54.8M 42.8M $61.8M 41.5M +1.3M +3.13% Add ALKERMES PLC ALKS
1.86% 2.82% $53.9M 1.0M $69.7M 2.0M -941,612 -47.78% Reduce E ERASCA INC ERAS
1.7% — $49.5M 2.7M $0 0 +2.7M New Buy NEUROPACE INC COM NPCE
1.59% 1.56% $46.3M 2.9M $38.6M 2.9M -21,085 -0.72% Reduce PROGYNY INC PGNY
1.59% 1.42% $46.2M 1.6M $35.1M 2.1M -465,000 -22.50% Reduce I INDIVIOR PHARMACEUTICALS INC INDV
1.5% 1.57% $43.7M 1.1M $38.8M 1.3M -210,000 -16.48% Reduce P PARABILIS MEDICINES INC PBLS
1.38% — $40.1M 1.5M $0 0 +1.5M New Buy E EDAP TMS S A FOCL
1.3% 1.1% $37.9M 7.3M $27.2M 7.3M 0 0.00% Unchanged GLOBUS MED INC GMED
1.28% 2.55% $37.0M 468,922 $62.9M 729,467 -260,545 -35.72% Reduce ARCUS BIOSCIENCES INC RCUS
1.24% 0.4% $36.0M 1.2M $9.8M 451,983 +716,755 +158.58% Add SYNDAX PHARMACEUTICALS INC SNDX
1.23% 1.63% $35.6M 1.6M $40.3M 1.7M -98,869 -5.73% Reduce NURIX THERAPEUTICS INC NRIX
1.22% 0.59% $35.5M 1.5M $14.5M 938,163 +527,000 +56.17% Add L LEGEND BIOTECH CORP LEGN
1.2% — $34.8M 1.2M $0 0 +1.2M New Buy JADE BIOSCIENCES INC JBIO
1.19% 0.45% $34.5M 1.6M $11.2M 796,744 +753,946 +94.63% Add UNITEDHEALTH GROUP INC UNH
1.15% — $33.3M 80,000 $0 0 +80,000 New Buy AVALO THERAPEUTICS AVTX
1.05% 0.27% $30.6M 1.7M $6.6M 441,978 +1.2M +274.45% Add U UROGEN PHARMA LTD URGN
1.05% 0.53% $30.5M 829,810 $13.1M 727,000 +102,810 +14.14% Add M MBX BIOSCIENCES INC MBX
0.98% 0.22% $28.4M 515,279 $5.3M 178,897 +336,382 +188.03% Add P PALISADE BIO INC PALI
0.94% — $27.3M 13.1M $0 0 +13.1M New Buy PHARVARIS N V PHVS
0.87% 0.8% $25.3M 730,907 $19.8M 702,052 +28,855 +4.11% Add O ORGANOGENESIS HLDGS INC COM ORGO
0.85% 0.97% $24.6M 10.1M $23.9M 10.1M +55,000 +0.55% Add SUPERNUS PHARMACEUTICALS SUPN
0.83% — $24.2M 520,000 $0 0 +520,000 New Buy PROCEPT BIOROBOTICS CORP PRCT
0.78% 0.16% $22.6M 1.0M $4.0M 160,000 +843,000 +526.88% Add T TANGO THERAPEUTICS INC TNGX
0.76% 0.38% $22.2M 709,000 $9.4M 450,000 +259,000 +57.56% Add I INHIBIKASE THERAPEUTICS INC COM NEW IKT
0.76% 0.74% $22.1M 10.9M $18.3M 10.9M 0 0.00% Unchanged TREVI THERAPEUTICS INC TRVI
0.76% 0.78% $22.0M 1.2M $19.3M 1.6M -440,382 -27.18% Reduce BIOMARIN PHARMACEUTICAL INC BMRN
0.74% 1.49% $21.5M 375,572 $36.8M 650,572 -275,000 -42.27% Reduce LIVANOVA PLC LIVN
0.72% 1.5% $21.0M 254,957 $37.0M 582,500 -327,543 -56.23% Reduce ARGENX SE SPONSORED ADR ARGX
0.64% 0.1% $18.5M 19,955 $2.6M 3,500 +16,455 +470.14% Add N NUVECTIS PHARMA INC COM NVCT
0.63% — $18.4M 1.0M $0 0 +1.0M New Buy C CAPRICOR THERAPEUTICS INC COM NEW CAPR
0.63% — $18.3M 761,737 $0 0 +761,737 New Buy EDGEWISE THERAPEUTICS INC EWTX
0.63% 1.85% $18.3M 450,889 $45.7M 1.4M -999,026 -68.90% Reduce P PRELUDE THERAPEUTICS INC COM PRLD
0.62% — $18.0M 3.4M $0 0 +3.4M New Buy XENON PHARMACEUTICALS INC XENE
0.56% 0.69% $16.1M 267,000 $17.0M 292,000 -25,000 -8.56% Reduce C C4 THERAPEUTICS INC COM STK CCCC
0.54% 0.41% $15.8M 3.4M $10.0M 3.8M -425,961 -11.20% Reduce K KINIKSA PHARMACEUTICALS INTL KNSA
0.54% 1.02% $15.8M 246,353 $25.1M 521,353 -275,000 -52.75% Reduce O ORTHOPEDIATRICS CORP COM KIDS
0.48% 0.4% $14.0M 732,144 $9.8M 615,447 +116,697 +18.96% Add A AVALYN PHARMACEUTICALS INC AVLN
0.48% — $13.8M 419,000 $0 0 +419,000 New Buy 
