 MADRIGAL PHARMACEUTICALS INCMDGL |
| 9.14% | 10.38% | $1.07B | 2.0M | $1.04B | 2.0M | 00.00% | Unchanged |
 ARGENX SE SPONSORED ADRARGX |
| 5.62% | 5.16% | $658.2M | 709,446 | $518.1M | 709,446 | 00.00% | Unchanged |
 PTC THERAPEUTICS INCPTCT |
| 5.39% | 5.25% | $631.9M | 7.7M | $527.8M | 7.7M | 00.00% | Unchanged |
| PPROTAGONIST THERAPEUTICS INCPTGX |
| 5.3% | 5.31% | $620.4M | 5.1M | $533.2M | 5.1M | +2,122+0.04% | Add |
 CG ONCOLOGY INCCGON |
| 5.16% | 4.7% | $605.0M | 8.5M | $472.7M | 7.0M | +1.5M+21.90% | Add |
 INSMED INCINSM |
| 4.41% | 7.88% | $516.3M | 4.8M | $791.9M | 4.8M | 00.00% | Unchanged |
| TTANGO THERAPEUTICS INCTNGX |
| 3.71% | 2.77% | $434.5M | 13.9M | $278.2M | 13.3M | +600,000+4.51% | Add |
| SSPYRE THERAPEUTICS INCSYRE |
| 3.22% | 2.09% | $377.5M | 4.3M | $210.4M | 4.2M | +80,000+1.92% | Add |
 CELCUITY INCCELC |
| 2.95% | 3.45% | $345.8M | 3.3M | $346.9M | 3.0M | +265,282+8.73% | Add |
| EERASCA INCERAS |
| 2.81% | 2.6% | $328.8M | 17.9M | $261.4M | 16.2M | +1.8M+11.08% | Add |
| RRADNET INCRDNT |
| 2.55% | 2.38% | $298.9M | 4.8M | $239.5M | 4.3M | +561,958+13.11% | Add |
| OORUKA THERAPEUTICS INC COMORKA |
| 2.55% | 1% | $298.7M | 3.1M | $101.0M | 2.1M | +1.1M+52.52% | Add |
 NATERA INCNTRA |
| 2.32% | 2.49% | $271.5M | 1.0M | $250.0M | 1.3M | -250,000-20.00% | Reduce |
| UULTRAGENYX PHARMACEUTICAL INRARE |
| 2.22% | 0.76% | $260.3M | 7.8M | $76.4M | 3.6M | +4.1M+113.68% | Add |
 IRHYTHM HOLDINGS INCIRTC |
| 2.22% | 1.96% | $259.6M | 2.2M | $196.9M | 1.7M | +514,131+30.81% | Add |
 CYTOKINETICS INCCYTK |
| 2.08% | 1.78% | $243.8M | 2.9M | $179.4M | 2.7M | +140,845+5.18% | Add |
| KKAILERA THERAPEUTICS INCKLRA |
| 2.03% | — | $237.4M | 10.8M | $0 | 0 | +10.8M | New Buy |
| EESTABLISHMENT LABS HLDGS INCESTA |
| 1.95% | 1.5% | $227.9M | 2.7M | $150.8M | 2.7M | 00.00% | Unchanged |
 GUARDANT HEALTH INCGH |
| 1.9% | 1.36% | $222.2M | 1.5M | $136.8M | 1.5M | 00.00% | Unchanged |
 NEUROCRINE BIOSCIENCES INCNBIX |
| 1.82% | 1.39% | $213.7M | 1.3M | $139.9M | 1.1M | +205,853+19.38% | Add |
| TTARSUS PHARMACEUTICALS INCTARS |
| 1.8% | 2.34% | $211.3M | 3.4M | $234.7M | 3.3M | +11,034+0.33% | Add |
 STOKE THERAPEUTICS INCSTOK |
| 1.57% | 1.82% | $184.0M | 5.6M | $183.1M | 5.6M | 00.00% | Unchanged |
 UNIQURE NVQURE |
| 1.55% | 0.42% | $181.5M | 3.9M | $42.3M | 2.6M | +1.4M+52.40% | Add |
| AACADIA PHARMACEUTICALS INC COMACAD |
| 1.54% | 1.58% | $180.8M | 7.1M | $159.0M | 7.1M | 00.00% | Unchanged |
| RREPLIGEN CORPRGEN |
| 1.45% | 1.41% | $169.3M | 1.2M | $142.1M | 1.2M | +34,637+2.87% | Add |
| UUROGEN PHARMA LTDURGN |
| 1.43% | 0.81% | $167.2M | 4.5M | $81.7M | 4.5M | 00.00% | Unchanged |
 GH RESEARCH PLC ORDINARY SHARESGHRS |
| 1.36% | 0.83% | $159.5M | 5.9M | $83.4M | 5.9M | 00.00% | Unchanged |
| IIMMUNOCORE HLDGS PLCIMCR |
| 1.32% | 1.46% | $154.6M | 4.9M | $146.8M | 4.9M | 00.00% | Unchanged |
 COMPASS PATHWAYS ADR A FUNSPONSORED ADR 1 ADR REPS 1 ORD SHSCMPS |
| 1.29% | 0.59% | $151.4M | 10.7M | $58.8M | 10.6M | +68,584+0.65% | Add |
 IMMATICS N.VIMTX |
| 1.12% | 1.26% | $131.1M | 12.9M | $126.6M | 12.9M | +76,836+0.60% | Add |
| ZZAI LAB LIMITED ADS EACH REP 10 ORD SHSZLAB |
| 1.07% | 1.23% | $124.9M | 6.6M | $123.7M | 6.6M | 00.00% | Unchanged |
| IIMMUNOVANT INCIMVT |
| 1.05% | 0.79% | $122.4M | 3.2M | $78.9M | 3.2M | 00.00% | Unchanged |
 BELITE BIO INCBLTE |
| 0.94% | 1.13% | $110.2M | 715,332 | $114.1M | 715,332 | 00.00% | Unchanged |
| XXENCOR INCXNCR |
| 0.93% | 0.81% | $109.1M | 6.8M | $81.7M | 6.8M | 00.00% | Unchanged |
 TAYSHA GENE THERAPIES INCTSHA |
| 0.79% | 0.61% | $92.3M | 13.6M | $61.2M | 13.7M | -119,990-0.88% | Reduce |
 COGENT BIOSCIENCES INCCOGT |
| 0.76% | 2.09% | $89.4M | 2.3M | $210.1M | 5.5M | -3.1M-57.70% | Reduce |
 ALKERMES PLCALKS |
| 0.75% | 0.59% | $87.6M | 1.7M | $59.1M | 1.7M | 00.00% | Unchanged |
 STRUCTURE THERAPEUTICS INCGPCR |
| 0.74% | — | $86.3M | 1.6M | $0 | 0 | +1.6M | New Buy |
| RREPLIMUNE GROUP INCREPL |
| 0.7% | 0.56% | $82.0M | 7.4M | $56.3M | 7.4M | +54,665+0.74% | Add |
| CCASTLE BIOSCIENCES INCCSTL |
| 0.57% | 0.67% | $66.3M | 2.8M | $67.7M | 2.8M | +20,000+0.73% | Add |
| CCANDEL THERAPEUTICS INC COMCADL |
| 0.56% | 0.31% | $66.1M | 6.4M | $31.5M | 6.4M | 00.00% | Unchanged |
 ROCKET PHARMACEUTICALS INC COMRCKT |
| 0.52% | 0.63% | $60.5M | 17.7M | $63.3M | 17.7M | 00.00% | Unchanged |
| KKODIAK SCIENCES INCKOD |
| 0.49% | 0.56% | $58.0M | 1.5M | $56.7M | 1.5M | 00.00% | Unchanged |
| AAKTIS ONCOLOGY INCAKTS |
| 0.44% | 0.28% | $51.3M | 1.6M | $28.5M | 1.6M | 00.00% | Unchanged |
 AXOGEN INCAXGN |
| 0.4% | — | $46.7M | 1.0M | $0 | 0 | +1.0M | New Buy |
 DANAHER CORP DEL COMDHR |
| 0.37% | — | $43.8M | 230,000 | $0 | 0 | +230,000 | New Buy |
| CCULLINAN THERAPEUTICS INCCGEM |
| 0.37% | 0.24% | $43.1M | 2.4M | $24.2M | 1.7M | +658,387+38.59% | Add |
| NNEUROGENE INC COMNGNE |
| 0.37% | 0.27% | $42.8M | 1.4M | $27.5M | 1.4M | 00.00% | Unchanged |
| HHINGE HEALTH INCHNGE |
| 0.35% | 0.74% | $41.5M | 500,000 | $74.4M | 1.9M | -1.4M-74.09% | Reduce |
| OORCHESTRA BIOMED HLDGS INC COMOBIO |
| 0.35% | 0.35% | $41.2M | 9.6M | $35.3M | 8.3M | +1.3M+15.05% | Add |
