 NATERA INCNTRA |
| 21.76% | 11.78% | $420.8M | 1.6M | $310.0M | 1.6M | 00.00% | Unchanged |
| VVERA THERAPEUTICS INCVERA |
| 6.2% | 4.27% | $119.9M | 2.8M | $112.4M | 2.8M | 00.00% | Unchanged |
| GGENMAB A/S SPONSORED ADSGMAB |
| 5.74% | 0.77% | $111.1M | 4.0M | $20.2M | 752,261 | +3.3M+437.74% | Add |
 JAZZ PHARMACEUTICALS PLCJAZZ |
| 4.55% | 4.3% | $88.0M | 365,341 | $113.1M | 598,327 | -232,986-38.94% | Reduce |
| RRAPPORT THERAPEUTICS INCRAPP |
| 4.1% | 2.26% | $79.4M | 1.9M | $59.6M | 1.9M | 00.00% | Unchanged |
| SSEAPORT THERAPEUTICS INCSPTX |
| 4% | — | $77.4M | 3.6M | $0 | 0 | +3.6M | New Buy |
| UULTRAGENYX PHARMACEUTICAL INRARE |
| 3.83% | 2.78% | $74.0M | 2.2M | $73.2M | 3.5M | -1.3M-36.57% | Reduce |
| AARRIVENT BIOPHARMA INCAVBP |
| 3.05% | 1.49% | $58.9M | 1.7M | $39.1M | 1.7M | 00.00% | Unchanged |
| BBIOAGE LABS INCBIOA |
| 2.91% | 1.52% | $56.2M | 2.3M | $40.1M | 2.3M | 00.00% | Unchanged |
 BRISTOL-MYERS SQUIBB COBMY |
| 2.61% | 4.58% | $50.5M | 876,970 | $120.6M | 2.0M | -1.1M-55.90% | Reduce |
 SUPERNUS PHARMACEUTICALSSUPN |
| 2.49% | 1.87% | $48.2M | 1.0M | $49.3M | 954,309 | +82,019+8.59% | Add |
 RHYTHM PHARMACEUTICALS INCRYTM |
| 2.34% | 1.49% | $45.3M | 408,027 | $39.1M | 450,096 | -42,069-9.35% | Reduce |
| GGILEAD SCIENCES INC COMGILD |
| 2.24% | — | $43.3M | 343,100 | $0 | 0 | +343,100 | New Buy |
 UNITED THERAPEUTICS CORP DELUTHR |
| 2.14% | 5.42% | $41.4M | 76,489 | $142.5M | 240,370 | -163,881-68.18% | Reduce |
 COGENT BIOSCIENCES INCCOGT |
| 2.07% | 3.09% | $40.1M | 1.0M | $81.4M | 2.1M | -1.1M-51.02% | Reduce |
 AXSOME THERAPEUTICS INC.AXSM |
| 2.03% | 2.65% | $39.3M | 160,429 | $69.8M | 412,747 | -252,318-61.13% | Reduce |
 IMMATICS N.VIMTX |
| 1.92% | 1.36% | $37.2M | 3.7M | $35.7M | 3.6M | +38,892+1.07% | Add |
| DDYNE THERAPEUTICS INCDYN |
| 1.9% | 1.13% | $36.8M | 1.7M | $29.6M | 1.6M | +24,487+1.50% | Add |
| IIMMUNOME INCIMNM |
| 1.88% | 1.41% | $36.5M | 1.7M | $37.2M | 1.7M | +18,412+1.08% | Add |
 IDEAYA BIOSCIENCES INCIDYA |
| 1.78% | 1.43% | $34.5M | 925,119 | $37.7M | 1.1M | -206,667-18.26% | Reduce |
| AANAPTYSBIO INCANAB |
| 1.72% | 0.52% | $33.3M | 493,536 | $13.8M | 248,253 | +245,283+98.80% | Add |
 NEKTAR THERAPEUTICS COM NEWNKTR |
| 1.7% | 1.39% | $32.9M | 471,763 | $36.7M | 509,546 | -37,783-7.42% | Reduce |
 PHARVARIS N VPHVS |
| 1.58% | 0.88% | $30.5M | 881,299 | $23.1M | 818,328 | +62,971+7.70% | Add |
 ARCUS BIOSCIENCES INCRCUS |
| 1.51% | 0.76% | $29.2M | 945,690 | $19.9M | 923,086 | +22,604+2.45% | Add |
 INHIBRX BIOSCIENCES INCINBX |
| 1.48% | 1.04% | $28.7M | 303,103 | $27.3M | 406,029 | -102,926-25.35% | Reduce |
 BIOMARIN PHARMACEUTICAL INCBMRN |
| 1.06% | 1.68% | $20.5M | 358,568 | $44.2M | 781,982 | -423,414-54.15% | Reduce |
| VVERADERMICS INCMANE |
| 0.95% | 0.18% | $18.3M | 148,993 | $4.6M | 73,315 | +75,678+103.22% | Add |
 ALCON AG ORD SHSALC |
| 0.89% | 2.09% | $17.2M | 255,824 | $55.0M | 729,972 | -474,148-64.95% | Reduce |
 INSMED INCINSM |
| 0.87% | 2.15% | $16.9M | 158,398 | $56.6M | 346,075 | -187,677-54.23% | Reduce |
 INTUITIVE SURGICAL INCISRG |
| 0.82% | — | $15.9M | 40,000 | $0 | 0 | +40,000 | New Buy |
 GLOBUS MED INCGMED |
| 0.82% | — | $15.8M | 200,000 | $0 | 0 | +200,000 | New Buy |
 EDGEWISE THERAPEUTICS INCEWTX |
| 0.8% | 0.46% | $15.5M | 380,923 | $12.2M | 386,498 | -5,575-1.44% | Reduce |
 EXELIXIS INCEXEL |
| 0.72% | 0.41% | $13.8M | 254,200 | $10.8M | 251,500 | +2,700+1.07% | Add |
 NURIX THERAPEUTICS INCNRIX |
| 0.66% | — | $12.7M | 524,098 | $0 | 0 | +524,098 | New Buy |
 DESIGN THERAPEUTICS INC COMDSGN |
| 0.65% | — | $12.5M | 865,135 | $0 | 0 | +865,135 | New Buy |
| DDEFINIUM THERAPEUTICS INCDFTX |
| 0.62% | 0.25% | $12.0M | 255,903 | $6.5M | 344,166 | -88,263-25.65% | Reduce |
| FFIRST TRACKS BIOTHERAPEUTICSTRAX |
| 0.59% | — | $11.4M | 565,199 | $0 | 0 | +565,199 | New Buy |
 ABBOTT LABORATORIESABT |
| 0.58% | — | $11.2M | 122,998 | $0 | 0 | +122,998 | New Buy |
 DISC MEDICINE INCIRON |
| 0.55% | 0.19% | $10.7M | 146,239 | $5.0M | 78,320 | +67,919+86.72% | Add |
| TTENAX THERAPEUTICS INCTENX |
| 0.38% | 0.06% | $7.3M | 500,039 | $1.7M | 104,400 | +395,639+378.96% | Add |
| SSIONNA THERAPEUTICS INCSION |
| 0.33% | — | $6.4M | 144,432 | $0 | 0 | +144,432 | New Buy |
| AABSCI CORPORATION COMABSI |
| 0.2% | — | $3.9M | 337,400 | $0 | 0 | +337,400 | New Buy |
| MMIRUM PHARMACEUTICALS INCMIRM |
| 0.17% | 0.1% | $3.2M | 27,591 | $2.5M | 27,591 | 00.00% | Unchanged |
 JADE BIOSCIENCES INCJBIO |
| 0.12% | 0.06% | $2.4M | 107,391 | $1.5M | 107,391 | 00.00% | Unchanged |
| SSAVARA INCSVRA |
| 0.12% | 0.08% | $2.2M | 364,763 | $2.0M | 364,763 | 00.00% | Unchanged |
 PRAXIS PRECISION MEDICINES IPRAX |
| 0.11% | 0.78% | $2.2M | 6,440 | $20.5M | 63,680 | -57,240-89.89% | Reduce |
| SSEPTERNA INCSEPN |
| 0.08% | 0.04% | $1.6M | 47,506 | $1.1M | 47,506 | 00.00% | Unchanged |
| OONKURE THERAPEUTICS INCOKUR |
| 0.08% | 0.02% | $1.5M | 321,692 | $586,638 | 141,700 | +179,992+127.02% | Add |
| SSAGIMET BIOSCIENCES INCSGMT |
| 0.07% | — | $1.3M | 166,667 | $0 | 0 | +166,667 | New Buy |
 WAVE LIFE SCIENCES LTDWVE |
| 0.06% | 0.05% | $1.1M | 189,253 | $1.4M | 189,253 | 00.00% | Unchanged |
