| RREVOLUTION MEDICINES INC COMRVMD |
| 10.1% | 6.93% | $207.0M | 1.1M | $117.6M | 1.2M | -104,255-8.62% | Reduce |
| TTRAVERE THERAPEUTICS INCTVTX |
| 6.04% | 2.59% | $123.8M | 2.2M | $43.9M | 1.5M | +701,115+47.44% | Add |
 ELI LILLY & COLLY |
| 5.78% | 5.35% | $118.4M | 98,700 | $90.8M | 98,700 | 00.00% | Unchanged |
 MADRIGAL PHARMACEUTICALS INCMDGL |
| 4.59% | 5.28% | $94.0M | 174,999 | $89.5M | 170,999 | +4,000+2.34% | Add |
| MMIRUM PHARMACEUTICALS INCMIRM |
| 4.56% | 4.42% | $93.4M | 798,145 | $74.9M | 811,294 | -13,149-1.62% | Reduce |
 RHYTHM PHARMACEUTICALS INCRYTM |
| 3.75% | 3.54% | $76.9M | 692,598 | $60.0M | 689,748 | +2,850+0.41% | Add |
 KYMERA THERAPEUTICS INCKYMR |
| 2.54% | 2.44% | $52.0M | 453,156 | $41.4M | 496,871 | -43,715-8.80% | Reduce |
 ARGENX SE SPONSORED ADRARGX |
| 2.39% | 4.24% | $48.9M | 52,750 | $71.9M | 98,500 | -45,750-46.45% | Reduce |
| AASCENDIS PHARMA A/S SPONSORED ADRASND |
| 2.2% | 2.62% | $45.0M | 168,750 | $44.4M | 194,000 | -25,250-13.02% | Reduce |
 XENON PHARMACEUTICALS INCXENE |
| 2.01% | 2.62% | $41.3M | 683,907 | $44.4M | 763,020 | -79,113-10.37% | Reduce |
 SCHOLAR ROCK HLDG CORPSRRK |
| 1.92% | 2.14% | $39.3M | 715,452 | $36.4M | 739,816 | -24,364-3.29% | Reduce |
 INSMED INCINSM |
| 1.88% | 3.03% | $38.6M | 362,150 | $51.4M | 314,300 | +47,850+15.22% | Add |
 PENUMBRA INCPEN |
| 1.78% | 2.33% | $36.5M | 115,750 | $39.6M | 120,500 | -4,750-3.94% | Reduce |
 STRUCTURE THERAPEUTICS INCGPCR |
| 1.68% | 1.82% | $34.4M | 640,317 | $30.9M | 640,217 | +100+0.02% | Add |
| UULTRAGENYX PHARMACEUTICAL INRARE |
| 1.58% | 1.5% | $32.3M | 967,855 | $25.5M | 1.2M | -250,918-20.59% | Reduce |
 IRHYTHM HOLDINGS INCIRTC |
| 1.57% | 1.82% | $32.1M | 269,650 | $30.9M | 261,750 | +7,900+3.02% | Add |
 INTUITIVE SURGICAL INCISRG |
| 1.48% | 2.23% | $30.4M | 76,460 | $37.8M | 82,000 | -5,540-6.76% | Reduce |
| AAGILON HEALTH INCAGL |
| 1.37% | 0.12% | $28.1M | 262,600 | $2.1M | 260,000 | +2,600+1.00% | Add |
 UNITEDHEALTH GROUP INCUNH |
| 1.29% | 0.85% | $26.5M | 63,750 | $14.3M | 53,000 | +10,750+20.28% | Add |
| CCELLDEX THERAPEUTICS INC NEWCLDX |
| 1.27% | 1.22% | $26.0M | 699,146 | $20.6M | 650,270 | +48,876+7.52% | Add |
| EERASCA INCERAS |
| 1.25% | 1.05% | $25.7M | 1.4M | $17.9M | 1.1M | +298,681+27.07% | Add |
 NEUROCRINE BIOSCIENCES INCNBIX |
| 1.19% | 1.17% | $24.4M | 144,750 | $19.8M | 150,450 | -5,700-3.79% | Reduce |
| EENLIVEN THERAPEUTICS INCELVN |
| 1.15% | 1.91% | $23.6M | 464,625 | $32.4M | 826,500 | -361,875-43.78% | Reduce |
| TTENET HEALTHCARE CORPTHC |
| 1.14% | 1.39% | $23.4M | 125,000 | $23.6M | 125,000 | 00.00% | Unchanged |
 DEXCOM INCDXCM |
| 1.13% | 1.32% | $23.1M | 343,000 | $22.3M | 355,600 | -12,600-3.54% | Reduce |
| AACLARIS THERAPEUTICS INC COMACRS |
| 1.12% | 0.99% | $22.9M | 4.3M | $16.8M | 4.5M | -142,118-3.18% | Reduce |
| MMINIMED GROUP INC COMMMED |
| 1.11% | 0.93% | $22.7M | 1.5M | $15.7M | 1.1M | +465,000+44.08% | Add |
 BOSTON SCIENTIFIC CORP COMBSX |
| 1.1% | 1.91% | $22.6M | 528,500 | $32.3M | 515,300 | +13,200+2.56% | Add |
 PHARVARIS N VPHVS |
| 1.09% | 1.07% | $22.4M | 648,333 | $18.2M | 645,533 | +2,800+0.43% | Add |
| AAVALYN PHARMACEUTICALS INCAVLN |
| 1.07% | — | $21.8M | 662,918 | $0 | 0 | +662,918 | New Buy |
| HHEMAB THERAPEUTICS HLDGS INCCOAG |
| 1.03% | — | $21.1M | 575,432 | $0 | 0 | +575,432 | New Buy |
| DDYNE THERAPEUTICS INCDYN |
| 1.02% | 1.04% | $20.9M | 942,154 | $17.6M | 972,198 | -30,044-3.09% | Reduce |
 ALNYLAM PHARMACEUTICALS INCALNY |
| 0.98% | 1.44% | $20.1M | 66,750 | $24.5M | 74,000 | -7,250-9.80% | Reduce |
 COGENT BIOSCIENCES INCCOGT |
| 0.97% | 1.42% | $20.0M | 515,917 | $24.0M | 624,155 | -108,238-17.34% | Reduce |
 AGIOS PHARMACEUTICALS INCAGIO |
| 0.96% | 1.59% | $19.8M | 532,563 | $27.0M | 799,163 | -266,600-33.36% | Reduce |
| NNEWAMSTERDAM PHARMA COMPANYNAMS |
| 0.96% | 1.11% | $19.7M | 582,744 | $18.8M | 588,794 | -6,050-1.03% | Reduce |
| VVERA THERAPEUTICS INCVERA |
| 0.9% | 1.19% | $18.3M | 427,584 | $20.3M | 503,585 | -76,001-15.09% | Reduce |
| TTARSUS PHARMACEUTICALS INCTARS |
| 0.85% | 0.93% | $17.4M | 277,087 | $15.8M | 225,179 | +51,908+23.05% | Add |
| HHEARTFLOW INCHTFL |
| 0.82% | 0.82% | $16.8M | 573,500 | $13.9M | 572,500 | +1,000+0.17% | Add |
| MMBX BIOSCIENCES INCMBX |
| 0.8% | 0.51% | $16.5M | 298,218 | $8.6M | 287,967 | +10,251+3.56% | Add |
 CYTOKINETICS INCCYTK |
| 0.78% | 0.18% | $16.0M | 187,980 | $3.0M | 45,364 | +142,616+314.38% | Add |
| BBICARA THERAPEUTICS INCBCAX |
| 0.78% | 0.57% | $15.9M | 535,286 | $9.7M | 489,095 | +46,191+9.44% | Add |
| PPARABILIS MEDICINES INCPBLS |
| 0.77% | — | $15.8M | 578,028 | $0 | 0 | +578,028 | New Buy |
| ZZAI LAB LIMITED ADS EACH REP 10 ORD SHSZLAB |
| 0.76% | 0.9% | $15.5M | 814,707 | $15.3M | 814,707 | 00.00% | Unchanged |
 DANAHER CORP DEL COMDHR |
| 0.71% | 0.69% | $14.5M | 76,300 | $11.7M | 61,500 | +14,800+24.07% | Add |
| TTANGO THERAPEUTICS INCTNGX |
| 0.7% | 0.48% | $14.3M | 456,551 | $8.1M | 386,915 | +69,636+18.00% | Add |
| EEVOLENT HEALTH INCEVH |
| 0.66% | 0.36% | $13.6M | 2.5M | $6.1M | 2.7M | -175,000-6.54% | Reduce |
 PTC THERAPEUTICS INCPTCT |
| 0.65% | 0.65% | $13.2M | 162,298 | $11.0M | 161,798 | +500+0.31% | Add |
 MINERALYS THERAPEUTICS INCMLYS |
| 0.64% | 0.7% | $13.1M | 484,951 | $11.9M | 439,751 | +45,200+10.28% | Add |
| ZZENAS BIOPHARMA INCZBIO |
| 0.62% | 0.58% | $12.7M | 502,077 | $9.8M | 502,077 | 00.00% | Unchanged |
