 PRAXIS PRECISION MEDICINES IPRAX |
| 10.88% | 14.33% | $214.3M | 640,000 | $285.3M | 885,500 | -245,500-27.72% | Reduce |
| BBRIDGEBIO ONCOLOGY THERAPEUTBBOT |
| 6.92% | 8.04% | $136.2M | 17.9M | $160.0M | 17.9M | 00.00% | Unchanged |
| PPARABILIS MEDICINES INCPBLS |
| 6.41% | — | $126.3M | 4.6M | $0 | 0 | +4.6M | New Buy |
| RRAPPORT THERAPEUTICS INCRAPP |
| 5.62% | 4.65% | $110.7M | 2.7M | $92.5M | 3.0M | -300,000-10.14% | Reduce |
| EERASCA INCERAS |
| 5.58% | 4.71% | $109.9M | 6.0M | $93.8M | 5.8M | +200,000+3.45% | Add |
 EDGEWISE THERAPEUTICS INCEWTX |
| 5.18% | 5.16% | $102.0M | 2.5M | $102.7M | 3.3M | -750,000-23.01% | Reduce |
| EEYEPOINT INCEYPT |
| 5.08% | 5.35% | $100.1M | 7.0M | $106.5M | 8.3M | -1.3M-15.31% | Reduce |
 ALUMIS INCALMS |
| 4.69% | 4.37% | $92.5M | 3.3M | $87.0M | 3.9M | -663,645-16.80% | Reduce |
 ABIVAX SAABVX |
| 4.57% | 4.25% | $90.0M | 675,000 | $84.6M | 760,000 | -85,000-11.18% | Reduce |
| DDIANTHUS THERAPEUTICS INCDNTH |
| 3.71% | 4% | $73.1M | 750,000 | $79.7M | 950,000 | -200,000-21.05% | Reduce |
| BBRIGHT MINDS BIOSCIENCES INCDRUG |
| 3.21% | 3.88% | $63.2M | 900,000 | $77.3M | 1.1M | -159,331-15.04% | Reduce |
| MMOONLAKE IMMUNOTHERAPEUTICSMLTX |
| 3.17% | 4.19% | $62.4M | 3.2M | $83.5M | 4.5M | -1.3M-28.46% | Reduce |
| BBIOAGE LABS INCBIOA |
| 2.98% | 2.54% | $58.6M | 2.4M | $50.6M | 2.9M | -500,000-17.30% | Reduce |
| OORUKA THERAPEUTICS INC COMORKA |
| 2.58% | 1.31% | $50.8M | 533,340 | $26.2M | 533,340 | 00.00% | Unchanged |
| AADLAI NORYTE LTDANL |
| 2.32% | 1.01% | $45.7M | 4.0M | $20.1M | 2.9M | +1.1M+37.28% | Add |
 BRIDGEBIO PHARMA INCBBIO |
| 2.08% | 3.17% | $41.0M | 550,000 | $63.1M | 850,000 | -300,000-35.29% | Reduce |
| TTANGO THERAPEUTICS INCTNGX |
| 2.06% | 1.5% | $40.6M | 1.3M | $29.8M | 1.4M | -125,000-8.77% | Reduce |
 BIOHAVEN LTDBHVN |
| 1.97% | 0.75% | $38.8M | 2.6M | $14.9M | 1.8M | +850,000+48.30% | Add |
| AAGOMAB THERAPEUTICS NV SPONSORED ADSAGMB |
| 1.62% | 1.3% | $32.0M | 2.5M | $25.9M | 2.5M | 00.00% | Unchanged |
| MMBX BIOSCIENCES INCMBX |
| 1.54% | 1.68% | $30.4M | 550,000 | $33.4M | 1.1M | -570,000-50.89% | Reduce |
| CCLIMB BIO INC COMCLYM |
| 1.39% | — | $27.5M | 2.1M | $0 | 0 | +2.1M | New Buy |
| OOLEMA PHARMACEUTICALS INC COMOLMA |
| 1.37% | 3.29% | $26.9M | 2.2M | $65.6M | 4.4M | -2.3M-51.14% | Reduce |
| DDAMORA THERAPEUTICS INCDMRA |
| 1.32% | 1.98% | $26.0M | 1.0M | $39.5M | 1.5M | -525,000-34.43% | Reduce |
 PHARVARIS N VPHVS |
| 1.32% | 1.42% | $25.9M | 750,000 | $28.3M | 1.0M | -250,000-25.00% | Reduce |
| FFAETH THERAPEUTICS INCFTH |
| 1.31% | 0.48% | $25.7M | 1.0M | $9.7M | 306,222 | +722,020+235.78% | Add |
 CORBUS PHARMACEUTICALS HLDGS COM NEWCRBP |
| 1.12% | 1.11% | $22.0M | 2.3M | $22.0M | 2.3M | 00.00% | Unchanged |
| SSPYRE THERAPEUTICS INCSYRE |
| 1.01% | — | $20.0M | 225,000 | $0 | 0 | +225,000 | New Buy |
| DDEFINIUM THERAPEUTICS INCDFTX |
| 0.96% | — | $18.8M | 400,000 | $0 | 0 | +400,000 | New Buy |
| NNEWAMSTERDAM PHARMA COMPANYNAMS |
| 0.86% | 1.53% | $16.9M | 500,000 | $30.4M | 950,000 | -450,000-47.37% | Reduce |
 ROIVANT SCIENCES LTDROIV |
| 0.85% | 1.04% | $16.8M | 475,000 | $20.8M | 750,000 | -275,000-36.67% | Reduce |
| CCABALETTA BIO INCCABA |
| 0.79% | 0.74% | $15.6M | 5.0M | $14.8M | 5.5M | -500,000-9.09% | Reduce |
| HHELIX ACQUISITION CORP IIIHLXC |
| 0.7% | 0.66% | $13.8M | 1.3M | $13.2M | 1.3M | 00.00% | Unchanged |
| AASCENDIS PHARMA A/S SPONSORED ADRASND |
| 0.68% | 1.09% | $13.3M | 50,000 | $21.7M | 95,000 | -45,000-47.37% | Reduce |
| KKAILERA THERAPEUTICS INCKLRA |
| 0.62% | — | $12.1M | 550,000 | $0 | 0 | +550,000 | New Buy |
 INSMED INCINSM |
| 0.41% | 1.56% | $8.0M | 75,000 | $31.1M | 190,000 | -115,000-60.53% | Reduce |
| EENLIVEN THERAPEUTICS INCELVN |
| 0.39% | — | $7.6M | 150,000 | $0 | 0 | +150,000 | New Buy |
| TTARSUS PHARMACEUTICALS INCTARS |
| 0.32% | 0.79% | $6.3M | 100,000 | $15.8M | 225,000 | -125,000-55.56% | Reduce |
| IIBIO INC CON NEWIBIO |
| 0.32% | — | $6.2M | 3.6M | $0 | 0 | +3.6M | New Buy |
| CCRINETICS PHARMACEUTICALS INCRNX |
| 0.24% | 0.46% | $4.7M | 125,000 | $9.1M | 250,000 | -125,000-50.00% | Reduce |
 ARCUTIS BIOTHERAPEUTICS INCARQT |
| 0.23% | 0.53% | $4.6M | 175,000 | $10.6M | 450,000 | -275,000-61.11% | Reduce |
 ARROWHEAD PHARMACEUTICALS INARWR |
| 0.21% | 0.31% | $4.1M | 50,000 | $6.3M | 100,000 | -50,000-50.00% | Reduce |
 STRUCTURE THERAPEUTICS INCGPCR |
| 0.2% | 0.42% | $4.0M | 75,000 | $8.4M | 175,000 | -100,000-57.14% | Reduce |
| RRESEARCH ALLIANCE CORP III |
| 0.2% | — | $4.0M | 370,000 | $0 | 0 | +370,000 | New Buy |
 COGENT BIOSCIENCES INCCOGT |
| 0.2% | 0.39% | $3.9M | 100,000 | $7.7M | 200,000 | -100,000-50.00% | Reduce |
 ALTIMMUNE INCALT |
| 0.19% | — | $3.8M | 1.3M | $0 | 0 | +1.3M | New Buy |
| AAMYLYX PHARMACEUTICALS INCAMLX |
| 0.18% | 0.24% | $3.6M | 200,000 | $4.9M | 350,000 | -150,000-42.86% | Reduce |
| OODYSSEY THERAPEUTICS INCODTX |
| 0.17% | — | $3.3M | 175,000 | $0 | 0 | +175,000 | New Buy |
 VAXCYTE INCPCVX |
| 0.15% | 0.29% | $2.9M | 50,000 | $5.8M | 100,000 | -50,000-50.00% | Reduce |
| BBOUNDLESS BIO INCBOLD |
| 0.13% | — | $2.5M | 1.0M | $0 | 0 | +1.0M | New Buy |
| QQUINCE THERAPEUTICS INCQNCX |
| 0.01% | — | $100,009 | 5,498 | $0 | 0 | +5,498 | New Buy |
