 INCYTE CORPINCY |
| 17.48% | 16.62% | $3.49B | 30.8M | $2.89B | 30.7M | +17,918+0.06% | Add |
| BBEONE MEDICINES LTDONC |
| 12.57% | 15% | $2.51B | 8.8M | $2.61B | 8.8M | +2,514+0.03% | Add |
| RREVOLUTION MEDICINES INC COMRVMD |
| 10.74% | 5.34% | $2.14B | 11.4M | $929.3M | 9.6M | +1.9M+19.76% | Add |
 MADRIGAL PHARMACEUTICALS INCMDGL |
| 5.77% | 6.44% | $1.15B | 2.1M | $1.12B | 2.1M | +1,430+0.07% | Add |
| AACADIA PHARMACEUTICALS INC COMACAD |
| 5.44% | 5.48% | $1.09B | 42.9M | $954.9M | 42.9M | +16,214+0.04% | Add |
 KYMERA THERAPEUTICS INCKYMR |
| 4.97% | 4.14% | $992.7M | 8.7M | $721.1M | 8.7M | 00.00% | Unchanged |
 INSMED INCINSM |
| 4.7% | 6.97% | $937.8M | 8.8M | $1.21B | 7.4M | +1.4M+18.53% | Add |
 CELCUITY INCCELC |
| 4.15% | 5.19% | $828.2M | 7.9M | $903.5M | 7.9M | 00.00% | Unchanged |
| KKODIAK SCIENCES INCKOD |
| 3.89% | 4.36% | $776.1M | 19.9M | $759.3M | 19.9M | 00.00% | Unchanged |
 RHYTHM PHARMACEUTICALS INCRYTM |
| 3.12% | 2.8% | $622.3M | 5.6M | $487.4M | 5.6M | 00.00% | Unchanged |
 PRAXIS PRECISION MEDICINES IPRAX |
| 2.94% | 3.24% | $587.0M | 1.8M | $564.9M | 1.8M | 00.00% | Unchanged |
 ALKERMES PLCALKS |
| 2.63% | 2.03% | $524.6M | 10.0M | $354.0M | 10.0M | 00.00% | Unchanged |
| SSUMMIT THERAPEUTICS INC COMSMMT |
| 2.39% | 3.96% | $477.7M | 32.8M | $690.0M | 36.4M | -3.6M-9.91% | Reduce |
 GRAIL INCGRAL |
| 1.38% | 1.2% | $275.0M | 4.0M | $208.2M | 4.0M | 00.00% | Unchanged |
| AABCELLERA BIOLOGICS INC COMABCL |
| 1.3% | 0.61% | $259.1M | 33.0M | $105.7M | 30.3M | +2.7M+9.04% | Add |
| IIMMUNOVANT INCIMVT |
| 1.05% | 0.78% | $209.4M | 5.4M | $135.6M | 5.5M | -22,661-0.42% | Reduce |
 IDEAYA BIOSCIENCES INCIDYA |
| 0.94% | 0.76% | $186.7M | 5.0M | $131.5M | 3.9M | +1.1M+26.95% | Add |
| KKINIKSA PHARMACEUTICALS INTLKNSA |
| 0.91% | 0.78% | $181.3M | 2.8M | $136.1M | 2.8M | +8,397+0.30% | Add |
 ROIVANT SCIENCES LTDROIV |
| 0.84% | 0.77% | $166.9M | 4.7M | $134.8M | 4.9M | -150,892-3.10% | Reduce |
 ARROWHEAD PHARMACEUTICALS INARWR |
| 0.81% | 0.72% | $162.4M | 2.0M | $124.9M | 2.0M | 00.00% | Unchanged |
 IONIS PHARMACEUTICALS INCIONS |
| 0.81% | 0.88% | $162.4M | 2.0M | $153.8M | 2.0M | 00.00% | Unchanged |
 EDGEWISE THERAPEUTICS INCEWTX |
| 0.75% | 1.19% | $150.4M | 3.7M | $207.1M | 6.6M | -2.9M-43.71% | Reduce |
| RREPLIMUNE GROUP INCREPL |
| 0.61% | 0.49% | $122.3M | 11.0M | $84.5M | 11.0M | 00.00% | Unchanged |
 NURIX THERAPEUTICS INCNRIX |
| 0.57% | 0.41% | $113.0M | 4.7M | $72.2M | 4.7M | 00.00% | Unchanged |
 STOKE THERAPEUTICS INCSTOK |
| 0.55% | 0.62% | $109.2M | 3.3M | $108.6M | 3.3M | 00.00% | Unchanged |
| MMONTE ROSA THERAPEUTICS INCGLUE |
| 0.53% | 0.41% | $105.2M | 4.3M | $71.5M | 4.3M | 00.00% | Unchanged |
 IMMATICS N.VIMTX |
| 0.48% | 0.62% | $96.3M | 9.5M | $107.4M | 10.9M | -1.4M-12.90% | Reduce |
 DENALI THERAPEUTICS INCDNLI |
| 0.48% | 0.41% | $96.0M | 3.7M | $71.6M | 3.7M | +2,641+0.07% | Add |
| CCRINETICS PHARMACEUTICALS INCRNX |
| 0.44% | 0.49% | $88.0M | 2.4M | $85.4M | 2.4M | 00.00% | Unchanged |
| DDIANTHUS THERAPEUTICS INCDNTH |
| 0.42% | 0.41% | $83.1M | 852,164 | $71.5M | 852,164 | 00.00% | Unchanged |
 STRUCTURE THERAPEUTICS INCGPCR |
| 0.39% | 0.4% | $76.9M | 1.4M | $69.0M | 1.4M | 00.00% | Unchanged |
| CCelcuity IncCELC |
| 0.35% | 0.43% | $69.2M | 30.8M | $74.9M | 30.8M | 00.00% | Unchanged |
| RRAPPORT THERAPEUTICS INCRAPP |
| 0.32% | 0.28% | $64.5M | 1.5M | $48.4M | 1.5M | 00.00% | Unchanged |
 ALUMIS INCALMS |
| 0.28% | 0.25% | $56.6M | 2.0M | $44.3M | 2.0M | 00.00% | Unchanged |
| PPRELUDE THERAPEUTICS INC COMPRLD |
| 0.27% | 0.2% | $54.0M | 10.1M | $34.6M | 10.1M | 00.00% | Unchanged |
 RELAY THERAPEUTICS INCRLAY |
| 0.27% | 0.07% | $52.9M | 2.8M | $11.5M | 1.2M | +1.7M+143.66% | Add |
| MMIRUM PHARMACEUTICALS INCMIRM |
| 0.26% | 0.24% | $52.2M | 445,975 | $41.2M | 445,975 | 00.00% | Unchanged |
 BICYCLE THERAPEUTICS PLC SPON ADS EACH REP 1 ORD SHSBCYC |
| 0.23% | 0.29% | $46.2M | 10.9M | $50.5M | 10.9M | 00.00% | Unchanged |
| EENLIVEN THERAPEUTICS INCELVN |
| 0.23% | 0.2% | $45.9M | 905,191 | $35.5M | 905,191 | 00.00% | Unchanged |
| CCELLDEX THERAPEUTICS INC NEWCLDX |
| 0.22% | 0.12% | $44.0M | 1.2M | $21.1M | 665,370 | +517,241+77.74% | Add |
| VVIRIDIAN THERAPEUTICS INCVRDN |
| 0.22% | 0.22% | $43.8M | 2.4M | $38.6M | 2.0M | +411,347+20.86% | Add |
 DESIGN THERAPEUTICS INC COMDSGN |
| 0.19% | 0.16% | $38.8M | 2.7M | $27.5M | 2.6M | +92,452+3.58% | Add |
 ENTRADA THERAPEUTICS INC COMTRDA |
| 0.19% | 0.37% | $37.3M | 5.1M | $64.0M | 5.1M | 00.00% | Unchanged |
| FFAETH THERAPEUTICS INCFTH |
| 0.16% | — | $32.2M | 1.3M | $0 | 0 | +1.3M | New Buy |
| AAKTIS ONCOLOGY INCAKTS |
| 0.16% | 0.1% | $32.1M | 996,351 | $17.8M | 996,351 | 00.00% | Unchanged |
| NNEUROGENE INC COMNGNE |
| 0.16% | 0.11% | $31.2M | 991,691 | $20.0M | 991,691 | 00.00% | Unchanged |
 JADE BIOSCIENCES INCJBIO |
| 0.14% | 0.13% | $27.3M | 1.2M | $23.1M | 1.6M | -410,711-25.03% | Reduce |
 TAYSHA GENE THERAPIES INCTSHA |
| 0.14% | 0.1% | $27.3M | 4.0M | $17.9M | 4.0M | 00.00% | Unchanged |
 ARCUS BIOSCIENCES INCRCUS |
| 0.13% | 0.05% | $26.0M | 844,816 | $9.0M | 415,621 | +429,195+103.27% | Add |
 DISC MEDICINE INCIRON |
| 0.13% | 0.13% | $25.6M | 349,657 | $22.4M | 349,657 | 00.00% | Unchanged |
