| RREVOLUTION MEDICINES INC COMRVMD |
| 9.48% | 9.55% | $194.1M | 4.3M | $194.1M | 4.3M | 00.00% | Unchanged |
| DDBV TECHNOLOGIES S A |
| 8.55% | 0.01% | $175.0M | 250,000 | $175,000 | 250,000 | 00.00% | Unchanged |
| NNUVALENT INCNUVL |
| 5.6% | 5.64% | $114.6M | 1.1M | $114.6M | 1.1M | 00.00% | Unchanged |
| BBEONE MEDICINES LTDONC |
| 5.48% | 5.53% | $112.3M | 500,000 | $112.3M | 500,000 | 00.00% | Unchanged |
 CYTOKINETICS INCCYTK |
| 5.42% | 5.46% | $110.9M | 2.1M | $110.9M | 2.1M | 00.00% | Unchanged |
| SSPRINGWORKS THERAPEUTICS INC COMSWTXUSD |
| 5.35% | 5.4% | $109.6M | 3.4M | $109.6M | 3.4M | 00.00% | Unchanged |
| MMERUS N V COM |
| 4.64% | 4.67% | $94.9M | 1.9M | $94.9M | 1.9M | 00.00% | Unchanged |
| TTYRA BIOSCIENCES INCTYRA |
| 4.41% | 7.46% | $90.3M | 6.4M | $151.6M | 6.4M | 00.00% | Unchanged |
 SAREPTA THERAPEUTICS INCSRPT |
| 3.96% | 4% | $81.2M | 650,000 | $81.2M | 650,000 | 00.00% | Unchanged |
 IDEAYA BIOSCIENCES INCIDYA |
| 3.41% | 3.44% | $69.8M | 2.2M | $69.8M | 2.2M | 00.00% | Unchanged |
 ARGENX SE SPONSORED ADRARGX |
| 2.65% | 2.67% | $54.2M | 100,000 | $54.2M | 100,000 | 00.00% | Unchanged |
| AAVIDITY BIOSCIENCES INC |
| 2.45% | 3.91% | $50.1M | 1.7M | $79.3M | 1.7M | 00.00% | Unchanged |
| AAPELLIS PHARMACEUTICALS INCAPLSUSD |
| 2.43% | 2.45% | $49.8M | 1.7M | $49.8M | 1.7M | 00.00% | Unchanged |
| AAKERO THERAPEUTICS INC COM |
| 2.35% | 2.37% | $48.1M | 1.7M | $48.1M | 1.7M | 00.00% | Unchanged |
 UNIQURE NVQURE |
| 1.96% | 0.54% | $40.1M | 2.2M | $11.0M | 2.2M | 00.00% | Unchanged |
 AXSOME THERAPEUTICS INC.AXSM |
| 1.76% | 1.77% | $35.9M | 400,000 | $35.9M | 400,000 | 00.00% | Unchanged |
 SCHOLAR ROCK HLDG CORPSRRK |
| 1.58% | 0.3% | $32.3M | 750,000 | $6.0M | 750,000 | 00.00% | Unchanged |
| IITEOS THERAPEUTICS INC COM |
| 1.47% | 1.48% | $30.1M | 2.9M | $30.1M | 2.9M | 00.00% | Unchanged |
| LLEGEND BIOTECH CORPLEGN |
| 1.43% | 1.44% | $29.2M | 600,000 | $29.2M | 600,000 | 00.00% | Unchanged |
| GGERON CORPGERN |
| 1.33% | 1.34% | $27.2M | 6.0M | $27.2M | 6.0M | 00.00% | Unchanged |
| TTHIRD HARMONIC BIO INC COM |
| 1.32% | 1.33% | $27.1M | 2.0M | $27.1M | 2.0M | 00.00% | Unchanged |
 ROCKET PHARMACEUTICALS INC COMRCKT |
| 1.32% | 1.33% | $27.1M | 1.5M | $27.1M | 1.5M | 00.00% | Unchanged |
| TTANGO THERAPEUTICS INCTNGX |
| 1.2% | 3.11% | $24.6M | 8.2M | $63.1M | 8.2M | 00.00% | Unchanged |
 ARCUS BIOSCIENCES INCRCUS |
| 1.2% | 1.21% | $24.5M | 1.6M | $24.5M | 1.6M | 00.00% | Unchanged |
 XENON PHARMACEUTICALS INCXENE |
| 1.15% | 1.16% | $23.6M | 600,000 | $23.6M | 600,000 | 00.00% | Unchanged |
| IIMMUNOVANT INCIMVT |
| 1.15% | 1.16% | $23.5M | 825,000 | $23.5M | 825,000 | 00.00% | Unchanged |
 KYMERA THERAPEUTICS INCKYMR |
| 1.04% | 1.05% | $21.3M | 450,000 | $21.3M | 450,000 | 00.00% | Unchanged |
| SSPYRE THERAPEUTICS INCSYRE |
| 1% | 1.01% | $20.5M | 696,480 | $20.5M | 696,480 | 00.00% | Unchanged |
| PPOSEIDA THERAPEUTICS INC |
| 0.98% | 0.28% | $20.0M | 2.0M | $5.7M | 2.0M | 00.00% | Unchanged |
| KKALVISTA PHARMACEUTICALS INC COM4XC1 |
| 0.9% | 0.91% | $18.4M | 1.6M | $18.4M | 1.6M | 00.00% | Unchanged |
| OORIC PHARMACEUTICALS INCORIC |
| 0.87% | 0.87% | $17.8M | 1.7M | $17.8M | 1.7M | 00.00% | Unchanged |
| EENLIVEN THERAPEUTICS INCELVN |
| 0.84% | 0.84% | $17.1M | 671,358 | $17.1M | 671,358 | 00.00% | Unchanged |
| AANAPTYSBIO INCANAB |
| 0.83% | 2.14% | $16.9M | 1.3M | $43.6M | 1.3M | 00.00% | Unchanged |
| RREPLIMUNE GROUP INCREPL |
| 0.82% | 0.83% | $16.8M | 1.5M | $16.8M | 1.5M | 00.00% | Unchanged |
| DDAY ONE BIOPHARMACEUTICALS INC COMDAWNGBX |
| 0.81% | 0.82% | $16.6M | 1.2M | $16.6M | 1.2M | 00.00% | Unchanged |
| CCULLINAN THERAPEUTICS INCCGEM |
| 0.74% | 0.75% | $15.2M | 907,895 | $15.2M | 907,895 | 00.00% | Unchanged |
 ARVINAS INCARVN |
| 0.73% | 0.74% | $15.0M | 608,614 | $15.0M | 608,614 | 00.00% | Unchanged |
 NURIX THERAPEUTICS INCNRIX |
| 0.62% | 0.62% | $12.7M | 563,067 | $12.7M | 563,067 | 00.00% | Unchanged |
 PROTHENA CORP PLCPRTA |
| 0.56% | 0.57% | $11.5M | 690,000 | $11.5M | 690,000 | 00.00% | Unchanged |
 STRUCTURE THERAPEUTICS INCGPCR |
| 0.53% | 0.86% | $10.8M | 400,000 | $17.6M | 400,000 | 00.00% | Unchanged |
 APOGEE THERAPEUTICS INCAPGE |
| 0.51% | 0.52% | $10.5M | 179,000 | $10.5M | 179,000 | 00.00% | Unchanged |
| FFATE THERAPEUTICS INC COMFATE |
| 0.48% | 0.85% | $9.9M | 5.0M | $17.4M | 5.0M | 00.00% | Unchanged |
| KKURA ONCOLOGY INCKURA |
| 0.44% | 0.96% | $9.0M | 1.0M | $19.5M | 1.0M | 00.00% | Unchanged |
| NNKARTA INC COMNKTX |
| 0.39% | 0.9% | $8.1M | 4.0M | $18.2M | 4.0M | 00.00% | Unchanged |
 RELAY THERAPEUTICS INCRLAY |
| 0.36% | 0.63% | $7.3M | 1.8M | $12.9M | 1.8M | 00.00% | Unchanged |
| IIOVANCE BIOTHERAPEUTICS INCIOVA |
| 0.34% | 0.35% | $7.0M | 750,000 | $7.0M | 750,000 | 00.00% | Unchanged |
| IInstil Bio IncTIL |
| 0.33% | 1.18% | $6.8M | 355,500 | $23.9M | 355,500 | 00.00% | Unchanged |
| JJASPER THERAPEUTICS INC COM NEWJSPRW |
| 0.32% | <0.01% | $6.6M | 350,000 | $6,584 | 350,000 | 00.00% | Unchanged |
| TTERNS PHARMACEUTICALS INC COM430 |
| 0.31% | 0.31% | $6.3M | 752,000 | $6.3M | 752,000 | 00.00% | Unchanged |
| SSUMMIT THERAPEUTICS INC COMSMMT |
| 0.27% | 0.27% | $5.5M | 250,000 | $5.5M | 250,000 | 00.00% | Unchanged |
