| AACADIA PHARMACEUTICALS INC COMACAD |
| 7.5% | 2.59% | $10.4M | 410,000 | $2.7M | 123,000 | +287,000+233.33% | Add |
 XERIS BIOPHARMA HLDGS INXERS |
| 7.04% | 5.63% | $9.7M | 1.2M | $5.9M | 1.0M | +205,000+20.00% | Add |
 BIOMARIN PHARMACEUTICAL INCBMRN |
| 5.94% | 4.39% | $8.2M | 143,500 | $4.6M | 82,000 | +61,500+75.00% | Add |
 PRAXIS PRECISION MEDICINES IPRAX |
| 5.46% | 13.13% | $7.5M | 22,550 | $13.9M | 43,050 | -20,500-47.62% | Reduce |
| UULTRAGENYX PHARMACEUTICAL INRARE |
| 4.95% | 3.46% | $6.8M | 205,000 | $3.7M | 174,250 | +30,750+17.65% | Add |
 AGIOS PHARMACEUTICALS INCAGIO |
| 4.4% | — | $6.1M | 164,000 | $0 | 0 | +164,000 | New Buy |
 INSMED INCINSM |
| 3.95% | — | $5.5M | 51,250 | $0 | 0 | +51,250 | New Buy |
| SSIONNA THERAPEUTICS INCSION |
| 3.91% | 1.87% | $5.4M | 123,000 | $2.0M | 49,200 | +73,800+150.00% | Add |
| CCRINETICS PHARMACEUTICALS INCRNX |
| 3.88% | — | $5.4M | 143,500 | $0 | 0 | +143,500 | New Buy |
| ZZENTALIS PHARMACEUTICALS INC COMZNTL |
| 3.59% | 2.72% | $5.0M | 1.0M | $2.9M | 1.2M | -205,000-16.67% | Reduce |
 VAXCYTE INCPCVX |
| 3.45% | 3.16% | $4.8M | 82,000 | $3.3M | 57,400 | +24,600+42.86% | Add |
 ANNEXON INCANNX |
| 3.38% | 0.91% | $4.7M | 820,000 | $965,345 | 174,250 | +645,750+370.59% | Add |
| TTRAVERE THERAPEUTICS INCTVTX |
| 3.37% | 3.11% | $4.7M | 82,000 | $3.3M | 110,700 | -28,700-25.93% | Reduce |
| TTONIX PHARMACEUTICALS HLDG CO COM NEWTNXP |
| 3.12% | — | $4.3M | 338,250 | $0 | 0 | +338,250 | New Buy |
 BRIDGEBIO PHARMA INCBBIO |
| 3.09% | — | $4.3M | 57,400 | $0 | 0 | +57,400 | New Buy |
 AXSOME THERAPEUTICS INC.AXSM |
| 2.9% | 6.56% | $4.0M | 16,400 | $6.9M | 41,000 | -24,600-60.00% | Reduce |
 CONTINEUM THERAPEUTICS INCCTNM |
| 2.43% | 1.76% | $3.4M | 205,000 | $1.9M | 142,000 | +63,000+44.37% | Add |
| LLEXICON PHARMACEUTICALS INC COM NEWLXRX |
| 2.21% | 1.33% | $3.1M | 1.3M | $1.4M | 902,000 | +369,000+40.91% | Add |
| KKURA ONCOLOGY INCKURA |
| 2.19% | — | $3.0M | 276,750 | $0 | 0 | +276,750 | New Buy |
 DBV TECHNOLOGIES S ADBVT |
| 2.19% | 2.03% | $3.0M | 184,500 | $2.1M | 102,500 | +82,000+80.00% | Add |
| GGENMAB A/S SPONSORED ADSGMAB |
| 2.04% | 2.08% | $2.8M | 102,500 | $2.2M | 82,000 | +20,500+25.00% | Add |
 CYTOKINETICS INCCYTK |
| 2.02% | — | $2.8M | 32,800 | $0 | 0 | +32,800 | New Buy |
 MINERALYS THERAPEUTICS INCMLYS |
| 2% | 2.1% | $2.8M | 102,500 | $2.2M | 82,000 | +20,500+25.00% | Add |
| NNUVATION BIO INCNUVB |
| 1.52% | — | $2.1M | 369,000 | $0 | 0 | +369,000 | New Buy |
 WAVE LIFE SCIENCES LTDWVE |
| 1.38% | — | $1.9M | 328,000 | $0 | 0 | +328,000 | New Buy |
 NEKTAR THERAPEUTICS COM NEWNKTR |
| 1.34% | — | $1.9M | 26,650 | $0 | 0 | +26,650 | New Buy |
 SCHOLAR ROCK HLDG CORPSRRK |
| 1.22% | 2.67% | $1.7M | 30,750 | $2.8M | 57,400 | -26,650-46.43% | Reduce |
| EENLIVEN THERAPEUTICS INCELVN |
| 1.2% | — | $1.7M | 32,800 | $0 | 0 | +32,800 | New Buy |
 ALNYLAM PHARMACEUTICALS INCALNY |
| 1.12% | 1.61% | $1.5M | 5,125 | $1.7M | 5,125 | 00.00% | Unchanged |
| BBEAM THERAPEUTICS INCBEAM |
| 1.02% | 1.29% | $1.4M | 41,000 | $1.4M | 57,400 | -16,400-28.57% | Reduce |
| OORIC PHARMACEUTICALS INCORIC |
| 0.96% | 1.23% | $1.3M | 123,000 | $1.3M | 102,500 | +20,500+20.00% | Add |
| NNEWAMSTERDAM PHARMA COMPANYNAMS |
| 0.9% | 1.12% | $1.3M | 36,900 | $1.2M | 36,900 | 00.00% | Unchanged |
 VERTEX PHARMACEUTICALS INCVRTX |
| 0.88% | — | $1.2M | 2,460 | $0 | 0 | +2,460 | New Buy |
| AARS PHARMACEUTICALS INCSPRY |
| 0.83% | — | $1.1M | 143,490 | $0 | 0 | +143,490 | New Buy |
| MMONOPAR THERAPEUTICS INCMNPR |
| 0.82% | — | $1.1M | 12,300 | $0 | 0 | +12,300 | New Buy |
| EERASCA INCERAS |
| 0.54% | — | $751,120 | 41,000 | $0 | 0 | +41,000 | New Buy |
| SSILENCE THERAPEUTICS PLCSLN |
| 0.44% | 0.7% | $608,850 | 55,350 | $740,435 | 140,500 | -85,150-60.60% | Reduce |
| VVERA THERAPEUTICS INCVERA |
| 0.32% | 3.12% | $439,828 | 10,250 | $3.3M | 82,000 | -71,750-87.50% | Reduce |
 IMMATICS N.VIMTX |
| 0.23% | 1.43% | $311,498 | 30,750 | $1.5M | 153,750 | -123,000-80.00% | Reduce |
| MMEREO BIOPHARMA GROUP FUNSPONSORED ADR 1 ADR REPS 5 ORD SHSMREO |
| 0.18% | — | $244,232 | 768,750 | $0 | 0 | +768,750 | New Buy |
| GGOSSAMER BIO INC COMGOSS |
| 0.1% | 0.26% | $134,972 | 820,000 | $269,370 | 820,000 | 00.00% | Unchanged |
