| SSTATE STREET SPDR S&P BIOTECH ETFXBI |
| 48.01% | 25.75% | $90.2M | 570,000 | $36.4M | 284,900 | +285,100+100.07% | Add |
| IISHARES TRSGOV |
| 37.51% | 49.86% | $70.5M | 700,000 | $70.5M | 700,000 | 00.00% | Unchanged |
 ROYALTY PHARMA PLCRPRX |
| 0.33% | 0.37% | $616,770 | 11,000 | $527,670 | 11,000 | 00.00% | Unchanged |
 NURIX THERAPEUTICS INCNRIX |
| 0.32% | 0.31% | $606,500 | 25,000 | $444,850 | 28,700 | -3,700-12.89% | Reduce |
 INCYTE CORPINCY |
| 0.32% | 0.35% | $600,808 | 5,300 | $498,836 | 5,300 | 00.00% | Unchanged |
 ARGENX SE SPONSORED ADRARGX |
| 0.32% | 0.33% | $594,701 | 641 | $468,090 | 641 | 00.00% | Unchanged |
 DISC MEDICINE INCIRON |
| 0.31% | 0.36% | $585,120 | 8,000 | $511,520 | 8,000 | 00.00% | Unchanged |
| RRAPPORT THERAPEUTICS INCRAPP |
| 0.31% | 0.31% | $583,380 | 14,000 | $438,060 | 14,000 | 00.00% | Unchanged |
| UULTRAGENYX PHARMACEUTICAL INRARE |
| 0.3% | 0.33% | $567,630 | 17,000 | $462,995 | 22,100 | -5,100-23.08% | Reduce |
 TREVI THERAPEUTICS INCTRVI |
| 0.3% | 0.25% | $559,500 | 30,000 | $357,900 | 30,000 | 00.00% | Unchanged |
| MMONTE ROSA THERAPEUTICS INCGLUE |
| 0.3% | 0.33% | $556,600 | 23,000 | $460,600 | 28,000 | -5,000-17.86% | Reduce |
 TG THERAPEUTICS INCTGTX |
| 0.29% | 0.31% | $549,400 | 10,000 | $431,860 | 13,000 | -3,000-23.08% | Reduce |
 HALOZYME THERAPEUTICS INCHALO |
| 0.29% | 0.37% | $547,890 | 7,000 | $518,720 | 8,026 | -1,026-12.78% | Reduce |
 IONIS PHARMACEUTICALS INCIONS |
| 0.29% | 0.36% | $539,172 | 6,800 | $510,612 | 6,800 | 00.00% | Unchanged |
 PHARVARIS N VPHVS |
| 0.28% | 0.4% | $518,700 | 15,000 | $565,000 | 20,000 | -5,000-25.00% | Reduce |
 ARCUTIS BIOTHERAPEUTICS INCARQT |
| 0.27% | 0.33% | $516,534 | 19,700 | $464,132 | 19,700 | 00.00% | Unchanged |
 AURINIA PHARMACEUTICALS INCAUPH |
| 0.27% | 0.31% | $509,100 | 30,000 | $444,600 | 30,000 | 00.00% | Unchanged |
 NEUROCRINE BIOSCIENCES INCNBIX |
| 0.27% | 0.36% | $505,605 | 3,000 | $506,936 | 3,848 | -848-22.04% | Reduce |
| IIMMUNOVANT INCIMVT |
| 0.27% | 0.34% | $500,890 | 13,000 | $476,928 | 19,200 | -6,200-32.29% | Reduce |
| AACADIA PHARMACEUTICALS INC COMACAD |
| 0.27% | 0.31% | $500,080 | 19,766 | $439,991 | 19,766 | 00.00% | Unchanged |
 PTC THERAPEUTICS INCPTCT |
| 0.26% | 0.29% | $489,420 | 6,000 | $408,780 | 6,000 | 00.00% | Unchanged |
| CCELLDEX THERAPEUTICS INC NEWCLDX |
| 0.26% | 0.29% | $483,730 | 13,000 | $412,360 | 13,000 | 00.00% | Unchanged |
| IIMMUNOCORE HLDGS PLCIMCR |
| 0.26% | 0.32% | $480,727 | 15,141 | $456,501 | 15,141 | 00.00% | Unchanged |
| DDEFINIUM THERAPEUTICS INCDFTX |
| 0.25% | 0.47% | $470,400 | 10,000 | $657,720 | 34,800 | -24,800-71.26% | Reduce |
 COGENT BIOSCIENCES INCCOGT |
| 0.25% | 0.33% | $464,400 | 12,000 | $461,880 | 12,000 | 00.00% | Unchanged |
 KYMERA THERAPEUTICS INCKYMR |
| 0.24% | 0.37% | $458,680 | 4,000 | $524,727 | 6,300 | -2,300-36.51% | Reduce |
| DDYNE THERAPEUTICS INCDYN |
| 0.24% | 0.26% | $444,200 | 20,000 | $362,600 | 20,000 | 00.00% | Unchanged |
 ALNYLAM PHARMACEUTICALS INCALNY |
| 0.23% | 0.34% | $441,009 | 1,465 | $484,725 | 1,465 | 00.00% | Unchanged |
| TTARSUS PHARMACEUTICALS INCTARS |
| 0.23% | 0.35% | $440,580 | 7,000 | $491,050 | 7,000 | 00.00% | Unchanged |
 SYNDAX PHARMACEUTICALS INCSNDX |
| 0.23% | 0.33% | $437,200 | 20,000 | $467,200 | 20,000 | 00.00% | Unchanged |
 EXELIXIS INCEXEL |
| 0.23% | 0.36% | $435,280 | 8,000 | $512,450 | 11,948 | -3,948-33.04% | Reduce |
| CCRINETICS PHARMACEUTICALS INCRNX |
| 0.22% | 0.28% | $411,620 | 11,000 | $399,520 | 11,000 | 00.00% | Unchanged |
| NNEWAMSTERDAM PHARMA COMPANYNAMS |
| 0.22% | 0.34% | $406,680 | 12,000 | $480,150 | 15,000 | -3,000-20.00% | Reduce |
| AASCENDIS PHARMA A/S SPONSORED ADRASND |
| 0.21% | 0.4% | $400,080 | 1,500 | $571,825 | 2,500 | -1,000-40.00% | Reduce |
 LIQUIDIA CORPORATIONLQDA |
| 0.21% | — | $398,650 | 5,000 | $0 | 0 | +5,000 | New Buy |
 STOKE THERAPEUTICS INCSTOK |
| 0.21% | 0.28% | $392,640 | 12,000 | $390,720 | 12,000 | 00.00% | Unchanged |
| VVIKING THERAPEUTICS INCVKTX |
| 0.21% | 0.35% | $390,100 | 10,000 | $488,100 | 15,000 | -5,000-33.33% | Reduce |
| IIMMUNOME INCIMNM |
| 0.2% | 0.31% | $381,420 | 18,000 | $437,400 | 20,000 | -2,000-10.00% | Reduce |
| PPROTAGONIST THERAPEUTICS INCPTGX |
| 0.2% | 0.22% | $367,740 | 3,000 | $316,200 | 3,000 | 00.00% | Unchanged |
 HARMONY BIOSCIENCES HLDGS INHRMY |
| 0.19% | 0.28% | $364,100 | 10,000 | $400,067 | 14,283 | -4,283-29.99% | Reduce |
| EENLIVEN THERAPEUTICS INCELVN |
| 0.19% | 0.19% | $355,250 | 7,000 | $274,400 | 7,000 | 00.00% | Unchanged |
| SSPYRE THERAPEUTICS INCSYRE |
| 0.19% | 0.18% | $355,120 | 4,000 | $260,220 | 5,159 | -1,159-22.47% | Reduce |
| IINTELLIA THERAPEUTICS INCNTLA |
| 0.18% | 0.24% | $338,400 | 20,000 | $344,858 | 26,900 | -6,900-25.65% | Reduce |
 MADRIGAL PHARMACEUTICALS INCMDGL |
| 0.17% | 0.22% | $322,170 | 600 | $314,082 | 600 | 00.00% | Unchanged |
| KKINIKSA PHARMACEUTICALS INTLKNSA |
| 0.17% | 0.31% | $319,750 | 5,000 | $433,350 | 9,000 | -4,000-44.44% | Reduce |
 ALKERMES PLCALKS |
| 0.17% | 0.15% | $314,370 | 6,000 | $212,160 | 6,000 | 00.00% | Unchanged |
| TTANGO THERAPEUTICS INCTNGX |
| 0.17% | 0.21% | $312,600 | 10,000 | $301,248 | 14,400 | -4,400-30.56% | Reduce |
| AARDELYX INCARDX |
| 0.16% | 0.34% | $306,000 | 60,000 | $479,200 | 80,000 | -20,000-25.00% | Reduce |
| VVERA THERAPEUTICS INCVERA |
| 0.16% | 0.28% | $300,370 | 7,000 | $402,300 | 10,000 | -3,000-30.00% | Reduce |
| MMIRUM PHARMACEUTICALS INCMIRM |
| 0.16% | 0.33% | $292,675 | 2,500 | $461,900 | 5,000 | -2,500-50.00% | Reduce |
