| RRELMADA THERAPEUTICS INCRLMD |
| 15.78% | 21.61% | $50.9M | 7.4M | $59.0M | 8.5M | -1.1M-13.27% | Reduce |
| CC4 THERAPEUTICS INC COM STKCCCC |
| 11.01% | 2.17% | $35.5M | 7.6M | $5.9M | 2.3M | +5.4M+237.78% | Add |
 COGENT BIOSCIENCES INCCOGT |
| 10.39% | 11.11% | $33.5M | 865,000 | $30.3M | 787,492 | +77,508+9.84% | Add |
| ZZENTALIS PHARMACEUTICALS INC COMZNTL |
| 6.21% | 3.46% | $20.0M | 4.1M | $9.4M | 4.0M | +95,000+2.36% | Add |
| KKODIAK SCIENCES INCKOD |
| 6.05% | 5.31% | $19.5M | 500,000 | $14.5M | 380,000 | +120,000+31.58% | Add |
 RELAY THERAPEUTICS INCRLAY |
| 5.63% | 3% | $18.1M | 970,000 | $8.2M | 822,500 | +147,500+17.93% | Add |
 EDGEWISE THERAPEUTICS INCEWTX |
| 3.66% | 4.04% | $11.8M | 290,000 | $11.0M | 350,000 | -60,000-17.14% | Reduce |
| MMAZE THERAPEUTICS INCMAZE |
| 3.1% | 2.82% | $10.0M | 335,000 | $7.7M | 257,500 | +77,500+30.10% | Add |
| BBIOAGE LABS INCBIOA |
| 3.08% | — | $9.9M | 405,000 | $0 | 0 | +405,000 | New Buy |
| IINVENTIVA SAIVA |
| 2.86% | 1.09% | $9.2M | 2.4M | $3.0M | 535,000 | +1.9M+355.14% | Add |
| AADLAI NORYTE LTDANL |
| 2.73% | 3.21% | $8.8M | 764,876 | $8.8M | 1.3M | -500,355-39.55% | Reduce |
 COMPASS PATHWAYS ADR A FUNSPONSORED ADR 1 ADR REPS 1 ORD SHSCMPS |
| 2.66% | — | $8.6M | 605,000 | $0 | 0 | +605,000 | New Buy |
| EENLIVEN THERAPEUTICS INCELVN |
| 2.52% | — | $8.1M | 160,000 | $0 | 0 | +160,000 | New Buy |
 REZOLUTE INCRZLT |
| 2.1% | — | $6.8M | 1.3M | $0 | 0 | +1.3M | New Buy |
| AARRIVENT BIOPHARMA INCAVBP |
| 1.97% | 0.93% | $6.4M | 183,000 | $2.5M | 110,000 | +73,000+66.36% | Add |
| PPALISADE BIO INCPALI |
| 1.95% | 1.92% | $6.3M | 3.0M | $5.3M | 3.0M | 00.00% | Unchanged |
| IINHIBIKASE THERAPEUTICS INC COM NEWIKT |
| 1.89% | 2.15% | $6.1M | 3.0M | $5.9M | 3.5M | -500,000-14.29% | Reduce |
| AADAGENE INCADAG |
| 1.63% | — | $5.3M | 1.3M | $0 | 0 | +1.3M | New Buy |
| FFORTE BIOSCIENCES INCFBRX |
| 1.48% | — | $4.8M | 225,000 | $0 | 0 | +225,000 | New Buy |
| IInflarx Nv |
| 1.39% | — | $4.5M | 2.0M | $0 | 0 | +2.0M | New Buy |
| AASSEMBLY BIOSCIENCES INCASMB |
| 1.36% | — | $4.4M | 160,000 | $0 | 0 | +160,000 | New Buy |
| PPROMIS NEUROSCIENCES INCPMN |
| 1.33% | 1.51% | $4.3M | 324,977 | $4.1M | 324,977 | 00.00% | Unchanged |
 CONTINEUM THERAPEUTICS INCCTNM |
| 1.32% | — | $4.3M | 260,000 | $0 | 0 | +260,000 | New Buy |
| DDEFINIUM THERAPEUTICS INCDFTX |
| 1.24% | — | $4.0M | 85,000 | $0 | 0 | +85,000 | New Buy |
| SSOL-GEL TECHNOLOGIES LTDSLGL |
| 1.2% | 0.9% | $3.9M | 52,000 | $2.5M | 31,000 | +21,000+67.74% | Add |
| SSCYNEXIS INCSCYX |
| 0.96% | 2.56% | $3.1M | 756,884 | $7.0M | 7.6M | -6.9M-90.05% | Reduce |
| PPROQR THRAPEUTICS N V |
| 0.87% | — | $2.8M | 1.5M | $0 | 0 | +1.5M | New Buy |
 DISC MEDICINE INCIRON |
| 0.68% | — | $2.2M | 30,000 | $0 | 0 | +30,000 | New Buy |
| LLIPOCINE INC NEW COM NEWLPCN |
| 0.64% | 1.32% | $2.1M | 810,000 | $3.6M | 450,000 | +360,000+80.00% | Add |
| UULTRAGENYX PHARMACEUTICAL INRARE |
| 0.57% | — | $1.8M | 55,000 | $0 | 0 | +55,000 | New Buy |
| CCUE BIOPHARMA INCCUE |
| 0.49% | — | $1.6M | 50,000 | $0 | 0 | +50,000 | New Buy |
| CCALCIMEDICA INCCALC |
| 0.4% | — | $1.3M | 1.2M | $0 | 0 | +1.2M | New Buy |
| QQUINCE THERAPEUTICS INCQNCX |
| 0.23% | — | $734,421 | 40,375 | $0 | 0 | +40,375 | New Buy |
| NNUVECTIS PHARMA INC COMNVCT |
| 0.22% | — | $711,693 | 38,700 | $0 | 0 | +38,700 | New Buy |
| PPASITHEA THERAPEUTICS CORPKTTA |
| 0.16% | 0.57% | $515,400 | 1.0M | $1.6M | 2.1M | -1.1M-52.38% | Reduce |
| IINMED PHARMACEUTICALS INCINM |
| 0.16% | — | $503,750 | 325,000 | $0 | 0 | +325,000 | New Buy |
| NNEUMORA THERAPEUTICS INC. COMNMRA |
| 0.05% | — | $170,000 | 100,000 | $0 | 0 | +100,000 | New Buy |
| NNEXTCURE INCNXTC |
| 0.03% | 1.04% | $103,142 | 64,464 | $2.8M | 265,000 | -200,536-75.67% | Reduce |
